Details of the Drug Combinations

General Information of This Drug (ID: DMKINJO)

Drug Name

Gentamicin DMKINJO

Synonyms

Alcomicin; Apogen; Bristagen; Cidomycin; GENTAMYCIN; Garamycin; Garasol; Gentacidin; Gentacycol; Gentafair; Gentak; Gentamar; Gentamicina; Gentamicine; Gentamicins; Gentamicinum; Gentamycinum; Gentavet; Gentocin; Jenamicin; Refobacin; Uromycine; Garamycin Otic Solution; Genoptic Liquifilm; Gentamcin Sulfate; Gentamicin sulphate sterile; Refobacin TM; Gentamicin C1; G-Mycin; G-Myticin; Garamycin (TN); Gentamicin (BAN); Gentamicin (TN); Gentamicina [INN-Spanish]; Gentamicine [INN-French]; Gentamicinum [INN-Latin];Gentamycin-creme; Gentamycin-creme [German]; Ocu-Mycin; Spectro-Genta; U-Gencin; Genoptic S.O.P.; O-2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-alpha-D-ribo-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-D-streptamine; (1R,2S,3S,4R,6S)-4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-beta-L-lyxo-heptopyranoside; (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl (6x)-2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-alpha-D-erythro-heptopyranoside; (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; 4,6-diamino-3-{[3-deoxy-4-c-methyl-3-(methylamino)pentopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside

Indication

Disease Entry	ICD 11	Status	REF
Bacteremia	1A73	Approved	[1]
Bacterial infection	1A00-1C4Z	Approved	[2]
Blepharoconjunctivitis	N.A.	Approved	[1]
Cholangitis	N.A.	Approved	[1]
Dacryocystitis	N.A.	Approved	[1]
Demodex blepharitis	1G07	Approved	[1]
Folliculitis	N.A.	Approved	[1]
Neonatal sepsis	N.A.	Approved	[1]
Paronychia	1F23.13	Approved	[1]
Peritonitis	N.A.	Approved	[1]
Pseudomonas aeruginosa infectious disease	N.A.	Approved	[1]
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Therapeutic Class

Antibiotics

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

8 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Ampicillin + Gentamicin	DCHJI8J	Ampicillin	Nephrolithiasis	[3]
Ampicillin + Gentamicin	DC7CAAS	Ampicillin	Premature Birth of Newborn	[4]
Dexamethasone + Gentamicin	DC9RQSR	Dexamethasone	Vestibular Disorder Preservation	[5]
Gentamicin + Mupirocin	DCLO2V2	Mupirocin	Peritoneal Dialysis-related Infection	[6]
Gentamicin + Azithromycin	DCQ7OW0	Azithromycin	Gonorrhoea	[7]
Ampicillin + Gentamicin	DCK8MBI	Ampicillin	Premature Birth	[8]
Gentamicin + Benzylpenicillin	DCSWFI2	Benzylpenicillin	Malnutrition Severe	[9]
Ornidazole + Gentamicin	DCR1H8M	Ornidazole	Colon Cancer	[10]
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⏷ Show the Full List of 8 DrugCom(s)

References

1	Gentamicin FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2427).
3	ClinicalTrials.gov (NCT02829060) Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
4	ClinicalTrials.gov (NCT02477423) A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome
5	ClinicalTrials.gov (NCT05355610) Vestibular Rehabilitation With Intratympanic Drug Therapy in Meniere's Disease
6	ClinicalTrials.gov (NCT05251584) Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection
7	ClinicalTrials.gov (NCT00926796) Efficacy of Combination Therapies for Gonorrhea Treatment
8	ClinicalTrials.gov (NCT05977400) NICU Antibiotics and Outcomes (NANO) Follow-up Study
9	ClinicalTrials.gov (NCT03174236) First Line Antimicrobials in Children With Complicated Severe Acute Malnutrition
10	ClinicalTrials.gov (NCT03475680) Mechanical Bowel Preparation and Oral Antibiotics Before Colon Cancer Surgery