Details of the Drug Combinations

General Information of This Drug (ID: DML2NIB)

Drug Name

Aminophylline DML2NIB

Synonyms

Aminocardol; Aminodur; Aminofilina; Aminofillina; Aminophyllin; Ammophyllin; Cardiofilina; Cardiomin; Cardophylin; Cardophyllin; Carena; Cariomin; DOBO; Diaphilline; Diaphyllin; Diaphylline; Diophllin; Diophyllin; Diuxanthine; Ethophylline; Eufilina; Euphyllin; Euphylline; Euphyllinum; Eurphyllin; Euufilin; Euufillin; Genophyllin; Grifomin; Inophylline; Lasodex; Linampheta; Lixaminol; Metaphyllin; Metaphylline; Minaphil; Miofilin; Neophyiline; Norofilina; Peterphyllin; Phylcardin; Phyllindon; Phyllocontin; Phyllotemp; Somophyllin; Stenovasan; Syntophyllin; Theodrox; Theolamine; Theolone; Theomin; Theophyldine; Thephyldine; Truphylline; Vasofilina; A 1755; BY 108; Minomal(TN); Phyllocontin (TN); TH/100; Truphylline (TN)

Indication

Disease Entry	ICD 11	Status	REF
Bronchial asthma	CA23	Approved	[1]
Bronchitis	CA20	Approved	[2]
Lung cancer	2C25.0	Approved	[2]
Non-small-cell lung cancer	2C25.Y	Approved	[2]
Pulmonary disease	1B10-1F85	Approved	[2]
Pulmonary emphysema	CA21.Z	Approved	[2]
Severe asthma	CA23	Approved	[2]
Asthma	CA23	Phase 2	[3]
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Therapeutic Class

Bronchodilator Agents

Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Aminophylline + Furosemide	DCX3BJ6	Furosemide	Acute Kidney Injury	[4]
Aminophylline + Furosemide	DCCPM87	Furosemide	Acute Kidney Injury	[5]
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References

1	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 081142.
2	Aminophylline FDA Label
3	Adenosine receptors: development of selective agonists and antagonists. Prog Clin Biol Res. 1987;230:41-63.
4	ClinicalTrials.gov (NCT02983422) Effects of Aminophylline on Renal Function and Urine Volume of AKI Patient
5	ClinicalTrials.gov (NCT05933642) Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults