Details of the Drug Combinations

General Information of This Drug (ID: DMM0HR1)

Drug Name
Pargyline   DMM0HR1
Synonyms
Benzylmethylpropargylamine; Benzylmethylpropynylamine; Eudatin; Eutron; Methylbenzylpropynylamine; Paragyline; Pargilina; Pargylamine; Pargylin; Pargylinum; Supirdyl; A 19120; MO 911; Pargilina [INN-Spanish]; Pargyline (INN); Pargyline [INN:BAN]; Pargylinum [INN-Latin]; Benzyl-methyl-2-propinylamin; Benzyl-methyl-2-propinylamin [Czech]; N-Methyl-N-benzylpropynylamine; N-Methyl-N-propargylbenzylamine; N-Methyl-N-2-propynylbenzylamine; N-Benzyl-N-methyl-2-propynylamine; N-Benzyl-N-methyl-2-propyn-1; N-Benzyl-N-methyl-2-propyn-1-amine; N-benzyl-N-methylprop-2-yn-1-amine; N-methyl-N-(phenylmethyl)prop-2-yn-1-amine
Indication
Disease Entry ICD 11 Status REF
Hypertension BA00-BA04 Approved [1]
Muscular dystrophy 8C70 Patented [2]
Skin imperfections EK71 Patented [2]
Therapeutic Class
Antihypertensive Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

52 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Aciclovir + Pargyline DCOEDBQ Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
BIO-300 + Pargyline DCJ3CZZ BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Clindamycin + Pargyline DCWIIIK Clindamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dantrolene + Pargyline DCP1AO3 Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diethylcarbamazine + Pargyline DC3IAA9 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Diphenidol + Pargyline DC2UR6F Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Docetaxel + Pargyline DC4J4D5 Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Emetine + Pargyline DCQ3Y8Y Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enalaprilat + Pargyline DCBFPFI Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Epinephrine + Pargyline DCRM11B Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fomepizole + Pargyline DCV00JF Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Imatinib + Pargyline DCJB979 Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
IT-141 + Pargyline DCVK014 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Itraconazole + Pargyline DCM2TWG Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Leflunomide + Pargyline DCOMPFO Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
LY03004 + Pargyline DC3Q6LP LY03004 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Pargyline DCX2PFU Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Pargyline DCPC4GY Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Memantine + Pargyline DCFTZWI Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methotrexate + Pargyline DCDXDOQ Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metyrosine + Pargyline DCN93GX Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Pargyline DCMTP9U Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Niclosamide + Pargyline DCZMSMV Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Baclofen DCAY4II Baclofen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Paromomycin DC2G4K6 Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Diethylcarbamazine DCHZLU0 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Dihydroergotamine DCETNN1 Dihydroergotamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Pepstatin DCSM421 Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Efavirenz DCFFEMD Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Carglumic acid DCAEQ7E Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Doxapram DCZXQB8 Doxapram Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Chlorzoxazone DC47Y3U Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Galantamine DCQCBAV Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + JZL195 DC5A2GC JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Clopidogrel DC3QTLV Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Isoproterenol DCEHXCS Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Tiagabine DCJLYFV Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + GINKGOLIDE A DCH69RZ GINKGOLIDE A Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Methylene blue DCNFJGR Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Trimethobenzamide DCBM6TY Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Chlorambucil DC435X2 Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Cisatracurium DCCMM46 Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Doxorubicin DC5V9Z2 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Nitisinone DCCTI79 Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Cerivastatin DCX6N80 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pargyline + Cytarabine DCARC7G Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PF-02545920 + Pargyline DCNLFCG PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PMID28460551-Compound-2 + Pargyline DCSFJ79 PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pyrazinamide + Pargyline DCN19JN Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Spironolactone + Pargyline DCWBAEF Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Terameprocol + Pargyline DCIM75I Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
WAY-100635 + Pargyline DCO67DG WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 52 DrugCom(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Novel monoamine oxidase inhibitors: a patent review (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):91-110.
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.