Details of the Drug Combinations | DrugMAP

General Information of This Drug (ID: DMN4H8N)

Drug Name

KAF156 DMN4H8N

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Phase 2	[1]
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Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Efavirenz + KAF156	DC4K36Z	Efavirenz	Malaria	[2]
Itraconazole + KAF156	DCMXVCB	Itraconazole	Malaria	[3]
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References

1	ClinicalTrials.gov (NCT01753323) Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection. U.S. National Institutes of Health.
2	ClinicalTrials.gov (NCT05330273) Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz
3	ClinicalTrials.gov (NCT05084651) Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole