Details of the Drug | DrugMAP

General Information of Drug (ID: DMN4H8N)

Drug Name

KAF156

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Phase 2	[1]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C22H23F2N5O
Canonical SMILES: CC1(C2=NC(=C(N2CCN1C(=O)CN)NC3=CC=C(C=C3)F)C4=CC=C(C=C4)F)C
InChI: 1S/C22H23F2N5O/c1-22(2)21-27-19(14-3-5-15(23)6-4-14)20(26-17-9-7-16(24)8-10-17)28(21)11-12-29(22)18(30)13-25/h3-10,26H,11-13,25H2,1-2H3
InChIKey: BUPRVECGWBHCQV-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 49856296
CAS Number: 1261113-96-5
TTD ID: D03QHC

Combinatorial Drugs (CBD)

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References

1	ClinicalTrials.gov (NCT01753323) Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection. U.S. National Institutes of Health.