Details of the Drug Combinations

General Information of This Drug (ID: DMOWLVG)

Drug Name
Nitazoxanide   DMOWLVG
Synonyms
Alinia; Colufase; Cryptaz; Daxon; Heliton; Nitazoxanid; Nitazoxanida; Nitazoxanidum; Taenitaz; Tizoxanide glucuronide; AZT + Nitazoxanide; Alinia (TN); Annita (TN); Azt+ nitazoxanide; Daxon (TN); Dexidex (TN); Kidonax (TN); Nitax (TN); Nitazox (TN); Nitazoxanida [INN-Spanish]; Nitazoxanide [USAN:INN]; Nitazoxanidum [INN-Latin]; Pacovanton (TN); Paramix (TN); Phavic-1; Zox (TN); Nitazoxanide (USAN/INN); Daxon, Dexidex, Kidonax, Pacovanton, Paramix, Nitax, Zox, Nitazoxanide
Indication
Disease Entry ICD 11 Status REF
Clostridioides difficile infection 1A04 Approved [1]
Cryptosporidium infection 1A32 Approved [1]
Diarrhea DA90 Approved [2]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 3 [3]
Giardiasis N.A. Investigative [1]
Therapeutic Class
Antiparasitic Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Nitazoxanide + Idarubicin DCMA5FD Idarubicin Glioblastoma? (Cell Line: T98G) [4]
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11 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Nitazoxanide + Oseltamivir DC46OTN Oseltamivir Influenza [5]
Nitazoxanide + Doxycycline DC4CA4D Doxycycline Sexually Transmitted Diseases [6]
Nitazoxanide + Dutasteride DCXCQLL Dutasteride Covid19 [7]
Nitazoxanide + Lactulose DC82K09 Lactulose Hepatic Encephalopathy [8]
Nitazoxanide + Favipiravir DCP4GGF Favipiravir Covid19 [9]
Nitazoxanide + Hydroxychloroquine DC2KPX7 Hydroxychloroquine Coronavirus Disease 2019 (COVID-19) [10]
Nitazoxanide + Clarithromycin DC6GJMF Clarithromycin Helicobacter-associated Gastritis [11]
Nitazoxanide + Norfloxacin DCLBY5P Norfloxacin Spontaneous Bacterial Peritonitis [12]
Nitazoxanide + Ivermectin DC4D4U5 Ivermectin Coronavirus Disease 2019 (COVID-19) [3]
Nitazoxanide + Ivermectin DCVPWKN Ivermectin Coronavirus Disease 2019 (COVID-19) [13]
Nitazoxanide + Hydroxychloroquine DCESWDP Hydroxychloroquine Coronavirus Infection [14]
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⏷ Show the Full List of 11 DrugCom(s)

References

1 Nitazoxanide FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 ClinicalTrials.gov (NCT04382846) Novel Regimens in COVID-19 Treatment. U.S. National Institutes of Health.
4 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
5 ClinicalTrials.gov (NCT01610245) Safety and Efficacy Study of Nitazoxanide in the Treatment of Acute Uncomplicated Influenza
6 ClinicalTrials.gov (NCT05897034) Combination Therapy Between Doxycycline, Pentoxifylline, and Nitazoxanide in Sexually Active Men
7 ClinicalTrials.gov (NCT04729491) EAT-DUTA AndroCoV Trial
8 ClinicalTrials.gov (NCT02334163) The Effects of Nitazoxanide in Hepatic Encephalopathy
9 ClinicalTrials.gov (NCT04918927) Favipiravir +/- Nitazoxanide: Early Antivirals Combination Therapy in COVID-19
10 ClinicalTrials.gov (NCT04361318) Hydroxychloroquine and Nitazoxanide Combination Therapy for COVID-19. U.S. National Institutes of Health.
11 ClinicalTrials.gov (NCT02422706) Study of Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori
12 ClinicalTrials.gov (NCT04746937) Nitazoxanide in Prevention of Secondary Spontaneous Peritonitis
13 ClinicalTrials.gov (NCT04360356) Ivermectin and Nitazoxanide Combination Therapy for COVID-19. U.S. National Institutes of Health.
14 ClinicalTrials.gov (NCT04341493) Hydroxychloroquine vs Nitazoxanide in Patients With COVID-19