Details of the Drug Combinations

General Information of This Drug (ID: DMQ9MVG)

• Drug Name: Chlorhexidine (DMQ9MVG)
• Synonyms: AVAGARD; Chlorhexidin; Chlorhexidinum; Cloresidina; Clorhexidina; Fimeil; Hexadol; Hibiclens; Hibispray; Hibistat;Nolvasan; Novalsan; Peridex; Periogard; Rotersept; Savloclens; Soretol; Sterido; Sterilon; Superspray; Tubulicid; Chlorhexidin [Czech]; Chlorhexidine Base; Chlorhexidine gluconate; Cloresidina [DCIT]; Decanoylacetaldehyde Sodium Sulfide; Dentisept [veterinary]; Savlon babycare; Sebidin A; Sodium Houttuyfonamide; Avagard (TN); BIOPATCH (TN); ChloraPrep (TN); Chlorhexamed (TN); Chlorhexidine (INN);Chlorhexidine [INN:BAN]; Chlorhexidinum [INN-Latin]; Chlorohex (TN); Clohex (TN); Clorexil (TN); Clorhexidina [INN-Spanish]; Corsodyl (TN); Dentisept [veterinary] (TN); Dexidin (TN); Exidine (TN); Hibiclens (TN); Hibiscrub (TN); MK-412A; Merfen-incolore; Oro-Clense; Oronine (TN); Perichlor (TN); Peridex (TN); Peridont (TN); Periochip (TN); Periogard Oral Rinse (TN); Perioxidina (TN); Savacol (TN); Suthol (TN); Dejavu-MW (TN); Merfen-incolore (TN); Lisium (*Dihydrochloride*); Nolvasan (*Diacetate*); SOLU-I.V (TN); N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide; N,N''''-hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)]; N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradeca-nediimidamide; N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)]; 1,1 inverted exclamation marka-Hexamethylenebis[5-(4-chlorophenyl)biguanide]; 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide); 1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide); 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide; 1,6-Bis(5-(p-chlorophenyl)biguandino)hexane; 1,6-Bis(p-chlorophenyldiguanido)hexane; 1,6-Di(4'-chlorophenyldiguanido)hexane; 1,6-Di(N-p-chlorophenyldiguanido)hexane

Indication

Bacterial infection; ICD 11: 1A00-1C4Z; Status: Approved [1]; Gingivitis; ICD 11: DA0B; Status: Approved [2]; Intracerebral hemorrhage; ICD 11: N.A.; Status: Approved [2]

• Therapeutic Class: Antibiotics
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

5 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Chlorhexidine + Mupirocin	DCIY0TV	Mupirocin	Staphylococcal Skin Infections	[3]
Povidone-iodine + Chlorhexidine	DCYXR41	Povidone-iodine	Staphylococcus Aureus	[4]
Povidone-iodine + Chlorhexidine	DC4CAAA	Povidone-iodine	Contraception	[5]
Chlorhexidine + Acetaminophen	DC0S4RS	Acetaminophen	Gingival Recession	[6]
Chlorhexidine + Amoxicillin	DCDAYAJ	Amoxicillin	Medication Related Osteonecrosis of the Jaw	[7]

References

• [1] FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019822.
• [2] Chlorhexidine FDA Label
• [3] ClinicalTrials.gov (NCT00731783) Staphylococcus Aureus Decolonization Study
• [4] ClinicalTrials.gov (NCT03173053) S. Aureus Decolonization in HPN Patients.
• [5] ClinicalTrials.gov (NCT02391714) Nitrous Oxide for Pain Management of Intrauterine Device (IUD) Insertion
• [6] ClinicalTrials.gov (NCT02433912) Clinical Evaluation of Single-stage Advanced Versus Rotated Flaps in the Treatment of Gingival Recessions
• [7] ClinicalTrials.gov (NCT04512638) Best Treatment Choice for Osteonecrosis of the Jaw