Details of the Drug Combinations

General Information of This Drug (ID: DMSVOCZ)

Drug Name

Pantoprazole DMSVOCZ

Synonyms

Astropan; Pantoprazol; Pantoprazolum; Pantoprozole; Pantor; Pantozol; Protium; Protonix; Somac; Pantoprazole Na; Pantoprazole Sodium; Protonix IV; BY 1023; Astropan (TN); BY-1023; Controloc (TN); Inipomp (TN); Pantecta (TN); Pantoloc (TN); Pantopan (TN); Pantoprazol [INN-Spanish]; Pantoprazolum [INN-Latin]; Pantor (TN); Pantotab (TN); Pantozol (TN); Protium (TN); Protonix (TN); SK&F 96022; SK-96022; SKF-96022; Somac (TN); Ulcepraz (TN); Pantoprazole (USAN/INN); Pantoprazole [USAN:BAN:INN]; SK&F-96022; 5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridyl)methyl)sulfinyl)benzimidazole; 5-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole

Indication

Disease Entry	ICD 11	Status	REF
Gastrinoma	2C10.1	Approved	[1]
Gastroesophageal reflux disease	DA22.Z	Approved	[2]
Peptic ulcer	DA61	Approved	[1]
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Therapeutic Class

Antiulcer Agents

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

14 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Cladribine + Pantoprazole	DC7S69E	Cladribine	Multiple Sclerosis	[3]
Clarithromycin + Pantoprazole	DCOMMIN	Clarithromycin	Helicobacter Pylori Infection	[4]
Clarithromycin + Pantoprazole	DCQ9MIX	Clarithromycin	Dyspepsia	[5]
Clarithromycin + Pantoprazole	DC8MTNA	Clarithromycin	Drug Interaction	[6]
F901318 + Pantoprazole	DCEO4FI	F901318	Invasive Aspergillosis	[7]
Levofloxacin + Pantoprazole	DCFQPL3	Levofloxacin	Melatonin Deficiency	[8]
Mycophenolate mofetil + Pantoprazole	DCZS0WL	Mycophenolate mofetil	Transplantation	[9]
Omeprazole + Pantoprazole	DCN28LH	Omeprazole	Acute Coronary Syndromes	[10]
Pantoprazole + Mycophenolic acid	DCEBDL2	Mycophenolic acid	Transplantation	[9]
Rebamipide + Pantoprazole	DC73ZBE	Rebamipide	Stomach Ulcer	[11]
Sitagliptin + Pantoprazole	DCLFHVF	Sitagliptin	Type 1 Diabetes	[12]
Aspirin + Pantoprazole	DCX1UOY	Aspirin	Psychosis	[13]
Levofloxacin + Pantoprazole	DCXGPBT	Levofloxacin	Helicobacter Pylori Infection	[14]
Omeprazole + Pantoprazole	DCIUVQM	Omeprazole	Coronary Artery Disease	[15]
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⏷ Show the Full List of 14 DrugCom(s)

References

1	Pantoprazole FDA Label
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7260).
3	ClinicalTrials.gov (NCT00938366) Drug-Drug Interaction of Cladribine and Pantoprazole in Multiple Sclerosis Subjects
4	ClinicalTrials.gov (NCT04621487) Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection
5	ClinicalTrials.gov (NCT04697641) Helicobacter Pylori Eradication in Functional Dyspepsia
6	ClinicalTrials.gov (NCT03011996) To Investigate PK and PD of CJ-12420, Clarithromycin, Amoxicillin After Multiple Dose Administration
7	ClinicalTrials.gov (NCT03095547) Drug/Drug Interactions With F901318
8	ClinicalTrials.gov (NCT04352062) Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia
9	ClinicalTrials.gov (NCT01801280) Influence of Pantoprazole on the Bioavailability of MMF and EC-MPS
10	ClinicalTrials.gov (NCT01735227) Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN)
11	ClinicalTrials.gov (NCT01167101) Is Rebamipide Effective on the Healing of Iatrogenic Gastric Ulcer After Endoscopic Mucosal Resection?
12	ClinicalTrials.gov (NCT00768651) Incretin Effect and Use After Clinical Islet Transplantation
13	ClinicalTrials.gov (NCT02685748) Aspirin in Young Psychotic Patients
14	ClinicalTrials.gov (NCT02466919) Study of Levofloxacin-based Concomitant Therapy for H. Pylori Eradication in Diabetic Patients
15	ClinicalTrials.gov (NCT02028234) "Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER-