Details of the Drug Combinations

General Information of This Drug (ID: DMTAJQE)

Drug Name
Amphotericin B   DMTAJQE
Synonyms
ABLC; Abelcet; Abelecet; Ambisome; Amphocin; Amphomoronal; Amphotec; Amphotericin; Amphotericinum; Amphotherizin; Amphozone; Fungilin; Fungisome; Fungisone; Fungizone; Halizon; SinuNase; Amfotericina B; Amophotericin B; Amphortericin B; Amphotericin B Cholesterol Dispersion; Amphotericin B Colloidal Dispersion; Amphotericin B liposomal; Amphotericin BETA; Amphotericine B; Amphotericinum B; Amphotherizin [German]; Liposomal Amphotericin B; NCI527017; NS 718; AMPH-B; Abelcet (TN); AmBisome (TN); Amfotericina B [INN-Spanish]; Ampho-Moronal; Amphocil (TN); Amphotec (TN); Amphotericin-B; Amphotericine B [INN-French]; Amphotericinum B [INN-Latin]; Fungilin (TN); Fungisome (TN); Fungizone (TN); LNS-AmB; Mysteclin-F; NKTR-024; Amphotericin B [USAN:INN:JAN]; Amphotericin B, Lipid-based; Amphotericin B, Streptomyces sp.; Amphotericin B (JP15/USP/INN)
Indication
Disease Entry ICD 11 Status REF
Acne vulgaris ED80 Approved [1]
Actinomycosis N.A. Approved [1]
Acute gonococcal cervicitis N.A. Approved [1]
Aspergillosis 1F20 Approved [1]
Blastomycosis 1F22 Approved [1]
Bronchitis CA20 Approved [1]
Brucellosis N.A. Approved [1]
Candidiasis 1F23 Approved [1]
Coccidioidomycosis 1F25 Approved [1]
Cryptococcal meningitis N.A. Approved [1]
Cryptococcosis N.A. Approved [1]
Cutaneous candidiasis 1F23.14 Approved [1]
Disseminated sporotrichosis N.A. Approved [1]
Fungal infection 1F29-1F2F Approved [2]
Histoplasmosis N.A. Approved [1]
Invasive candidiasis 1F23 Approved [1]
Leishmaniasis 1F54 Approved [1]
Lymphogranuloma venereum N.A. Approved [1]
Mycotic endocarditis N.A. Approved [1]
Oral candidiasis 1F23.0 Approved [1]
Ornithosis N.A. Approved [1]
Pneumonia CA40 Approved [1]
Q fever N.A. Approved [1]
Relapsing fever N.A. Approved [1]
Rickettsialpox N.A. Approved [1]
Rocky mountain spotted fever N.A. Approved [1]
Syphilis N.A. Approved [1]
Trachoma N.A. Approved [1]
Typhus N.A. Approved [1]
Urinary tract infection GC08 Approved [1]
Yaws N.A. Approved [1]
Candidemia 1F23.3Y Investigative [1]
Esophageal candidiasis N.A. Investigative [1]
Mycoses 1F2Z Investigative [3]
Pelvic inflammatory disease GA05 Investigative [1]
Sinusitis CA0A.Z Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antifungal Agents
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

4 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Fluconazole + Amphotericin B DCPVWQW Fluconazole Cryptococcal Meningitis [4]
Flucytosine + Amphotericin B DCITR0Y Flucytosine Cryptococcal Meningitis [5]
Citalopram + Amphotericin B DCAWEAQ Citalopram Major Depressive Disorder [6]
Voriconazole + Amphotericin B DCZ2RUT Voriconazole Blastomycosis [7]
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References

1 Amphotericin B FDA Label
2 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 050724.
3 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
4 ClinicalTrials.gov (NCT00145249) Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis
5 ClinicalTrials.gov (NCT04140461) AmB Dose for Cryptococcal Meningitis
6 ClinicalTrials.gov (NCT04975724) Safety of Liposom With Citalopram in Elderly Patients With Major Depressive Disorder
7 ClinicalTrials.gov (NCT02283905) Amphotericin-B and Voriconazole for Pulmonary Blastomycosis