Details of the Drug Combinations

General Information of This Drug (ID: DMU8V4S)

Drug Name
Moxifloxacin   DMU8V4S
Synonyms
Avelox; MFX; MXF; MXFX; Vigamox; Avalox (TN); Avelon (TN); Avelox (TN); Moxifloxacin [INN:BAN]; Vigamox (TN); Avelox I.V.; Actira (*Hydrochloride*); Avelox (*Hydrochloride*); (1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid; 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Bacterial infection 1A00-1C4Z Approved [1]
Mycoplasma pneumoniae pneumonia N.A. Approved [2]
Peritonitis N.A. Approved [2]
Pneumonic plague N.A. Approved [2]
Septicemic plague N.A. Approved [2]
Staphylococcal pneumonia N.A. Approved [2]
Staphylococcus aureus infection N.A. Approved [2]
Streptococcal pneumonia N.A. Approved [2]
Tuberculosis 1B10-1B14 Approved [2]
Pneumonia caused by chlamydia N.A. Investigative [2]
Pneumonia due to Klebsiella pneumoniae CA40.03 Investigative [2]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

15 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Celecoxib + Moxifloxacin DCH63Z4 Celecoxib Qt Interval, Variation in [3]
Dexamethasone + Moxifloxacin DCC48IL Dexamethasone Blepharitis [4]
Diltiazem + Moxifloxacin DCGDPFZ Diltiazem Drug-induced QT Prolongation [5]
Diphenhydramine + Moxifloxacin DCRG9G1 Diphenhydramine Cancer [6]
Gatifloxacin + Moxifloxacin DCX5JJ1 Gatifloxacin Bacterial Conjunctivitis [7]
Linezolid + Moxifloxacin DCKZGIW Linezolid Skin Diseases, Infectious [8]
Omaveloxolone + Moxifloxacin DC16REB Omaveloxolone Health Adult Subjects [9]
Pazopanib + Moxifloxacin DCWOC84 Pazopanib Carcinoma, Renal Cell [10]
Pretomanid + Moxifloxacin DCW5NJK Pretomanid Pulmonary Tuberculosis [11]
Rifapentine + Moxifloxacin DC81JE9 Rifapentine Mycobacterium Tuberculosis [12]
Vancomycin + Moxifloxacin DCBU8D8 Vancomycin Peritoneal Dialysis Associated Peritonitis [13]
Bedaquiline + Moxifloxacin DCDV78F Bedaquiline Tuberculosis, Pulmonary [14]
Bedaquiline + Moxifloxacin DCVMZGP Bedaquiline Pulmonary Tuberculosis [15]
Linezolid + Moxifloxacin DCBUPAP Linezolid Community Acquired Pneumonia [16]
Esomeprazole + Moxifloxacin DC48T1G Esomeprazole Helicobacter Infections [17]
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⏷ Show the Full List of 15 DrugCom(s)

References

1 Novel agents in the management of Mycobacterium tuberculosis disease. Curr Med Chem. 2007;14(18):2000-8.
2 Moxifloxacin FDA Label
3 ClinicalTrials.gov (NCT03822520) Clinical Study to Evaluate Effect on QT/QTc Interval After Multiple Dose of Celecoxib
4 ClinicalTrials.gov (NCT00732446) Safety/Efficacy of Antibiotic Steroid Combination in Treatment of Blepharitis and/or Keratitis and/or Conjunctivitis
5 ClinicalTrials.gov (NCT02308748) Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block
6 ClinicalTrials.gov (NCT01017731) Study of Ramucirumab (IMC-1121B) Therapy and Corrected QT (QTc) Interval Changes
7 ClinicalTrials.gov (NCT00464438) A Study to Evaluate the Safety and Efficacy of Gatifloxacin for the Treatment of Bacterial Conjunctivitis
8 ClinicalTrials.gov (NCT00865280) Study the Safety and Efficacy of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI). U.S. National Institutes of Health.
9 ClinicalTrials.gov (NCT05927649) A TQTc Study for Omaveloxolone
10 ClinicalTrials.gov (NCT00861029) VEG111485: A QTc Study of Pazopanib
11 ClinicalTrials.gov (NCT01215851) Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001)
12 ClinicalTrials.gov (NCT00460759) Pharmacokinetic Issues of Moxifloxacin Plus Rifapentine
13 ClinicalTrials.gov (NCT02787057) Vancomycin Plus Moxifloxacin Versus Vancomycin Plus Ceftazidime for the Treatment of Peritoneal Dialysis (PD)-Related Peritonitis
14 ClinicalTrials.gov (NCT05926466) BTZ-043 Dose Evaluation in Combination and Selection
15 ClinicalTrials.gov (NCT06114628) Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB
16 ClinicalTrials.gov (NCT02559310) Study to Compare Lefamulin to Moxifloxacin (With or Without Linezolid) for the Treatment of Adults With Pneumonia
17 ClinicalTrials.gov (NCT01792700) Long-term Follow up Helicobacter Pylori Reinfection Rate After Second-Line Treatment: Bismuth-Containing Quadruple Therapy Versus Moxifloxacin-Based Triple Therapy