Details of the Drug Combinations

General Information of This Drug (ID: DMVO0UB)

• Drug Name: Alfentanil (DMVO0UB)
• Synonyms: Alfenta; Alfentanilum; Alfentanyl; Alfenta (TN); Alfentanil (INN); Alfentanil [INN:BAN]; Alfentanilum [INN-Latin]; Rapifen (TN); N-[1-[2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl]-4-(methoxymethyl)-4-piperidyl]propionanilide; N-[1-[2-(4-ethyl-5-oxotetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl]-N-phenylpropanamide; N-(1-(2-(4-Ethyl-4,5-dihydro-5-oxotetrazolyl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilid; N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilide; N-(1-(2-(4-Ethyl-4,5-dihydro-5-oxotetrazolyl)ethyl)-4-(methoxymethyl)-4-piperidyl)-N-phenylpropionamid; N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide; N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl]-4-[(methyloxy)methyl]piperidin-4-yl}-N-phenylpropanamide

Indication

Anaesthesia; ICD 11: 9A78.6; Status: Approved [1]

• Therapeutic Class: Anesthetics
• Drug Type: Small molecular drug

List of Combinatorial Drugs (CBD) Containing This Drug

7 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Desflurane + Alfentanil	DCIH3MU	Desflurane	Cerebral Ischemia	[2]
Propofol + Alfentanil	DCCT8DH	Propofol	Cerebral Ischemia	[2]
Propofol + Alfentanil	DCGNM8B	Propofol	Pharmacodynamics	[3]
Propofol + Alfentanil	DC1WNDE	Propofol	Lung Disease	[4]
Propofol + Alfentanil	DCWO6MQ	Propofol	Sedation	[5]
Thiopental + Alfentanil	DC5HTF8	Thiopental	Adverse Effect of Other General Anesthetics	[6]
Alfentanil + Midazolam	DCG1CV6	Midazolam	Emergence Agitation	[7]

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7108).
• [2] ClinicalTrials.gov (NCT01436799) Desflurane Versus Propofol in the Sitting Position
• [3] ClinicalTrials.gov (NCT03813875) Modeling and Application of Triple Drug Response Surface Models
• [4] ClinicalTrials.gov (NCT02000206) Comparison of Propofol/Alfentanil With Propofol/Ketamine
• [5] ClinicalTrials.gov (NCT00997113) Stress During Deep Sedation With Propofol With and Without Alfentanil
• [6] ClinicalTrials.gov (NCT02486926) The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children
• [7] ClinicalTrials.gov (NCT02022488) Sevoflurane Induced Emergence Agitation