Details of the Drug Combinations

General Information of This Drug (ID: DMWIJTN)

Drug Name

Voclosporin DMWIJTN

Synonyms

Luveniq; ISAtx-247; ISA-247; UNII-2PN063X6B1; ISATX247; 515814-01-4; ISA247; 2PN063X6B1; ISA 247; trans-ISA-247; LX211; Voclosporin (USAN/INN); Voclosporin [USAN:INN]; Voclera; 3odi; LX-211; LX-214; ISA247, Luveniq; AC1OCFHS; R-1524; SCHEMBL12632344; CHEBI:135957; (E)-ISA-247; DB11693; 515814-00-3; HY-106638; CS-0026210; D09033; Cyclosporin A, 6-((2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid)-; 368455-04-3; Luveniq; Voclosporin [USAN]; R 1524; Trans-ISA 247; Trans-ISA-247; TrkA-IgG

Indication

Disease Entry	ICD 11	Status	REF
Lupus nephritis	4A40.0Y	Approved	[1]
Psoriasis vulgaris	EA90	Phase 3	[2]
Kidney disease	GC2Z	Phase 2	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Simvastatin + Voclosporin	DC3YCER	Simvastatin	Drug-drug Interaction	[3]
Mycophenolate mofetil + Voclosporin	DC4ZMYY	Mycophenolate mofetil	Systemic Lupus Erythematosus	[4]
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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2021
2	Emerging drugs for psoriasis. Expert Opin Emerg Drugs. 2009 Mar;14(1):145-63.
3	ClinicalTrials.gov (NCT05306379) Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin
4	ClinicalTrials.gov (NCT05306873) Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus