Details of the Drug Combinations

General Information of This Drug (ID: DMXE76K)

Drug Name

Delamanid DMXE76K

Synonyms

OPC-67683; Nitro-dihydroimidazo-oxazole derivatives (tuberculosis), Otsuka; 2-nitroimidazole derivatives (tuberculosis), Otsuka

Indication

Disease Entry	ICD 11	Status	REF
Multi-drug resistant tuberculosis	MG52.00	Approved	[1]
Mycobacterium infection	1B10-1B21	Phase 3	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Bedaquiline + Delamanid	DCTDKUM	Bedaquiline	Tuberculosis	[3]
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References

1	Compassionate use of delamanid in adults and children for drug-resistant tuberculosis: 5-year update. Eur Respir J. 2021 May 20;57(5):2002483.
2	ClinicalTrials.gov (NCT01424670) Safety and Efficacy Trial of Delamanid for 6 Months in Patients With Multidrug Resistant Tuberculosis. U.S. National Institutes of Health.
3	ClinicalTrials.gov (NCT05382312) Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis