Details of the Drug Combinations

General Information of This Drug (ID: DMZ80SB)

Drug Name
Azatadine   DMZ80SB
Synonyms
Azatadina; Azatadinum; Azatidine; Azatadine maleate; Azatadina [INN-Spanish]; Azatadine (INN); Azatadine [INN:BAN]; Azatadinum [INN-Latin]; 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
Indication
Disease Entry ICD 11 Status REF
Allergic rhinitis CA08.0 Approved [1]
Common cold CA00 Approved [2]
Seasonal allergic rhinitis CA08.01 Approved [2]
Urticaria EB00-EB05 Approved [2]
Vasomotor/allergic rhinitis CA08 Approved [2]
Pruritus EC90 Investigative [2]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antihistamines
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

61 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
10-hydroxycamptothecin + Azatadine DC3SLHS 10-hydroxycamptothecin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acamprosate + Azatadine DC35XCV Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Aprepitant DCRZHZ2 Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Bepridil DCY5S65 Bepridil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + GYKI-52466 DC98M3M GYKI-52466 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Ramelteon DCT1TDB Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Triapine DCF09UC Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Acitretin DC83KRJ Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + IT-141 DCO3WK5 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + SCH 727965 DCY3WEV SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Chlorzoxazone DCEXNLQ Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Docetaxel DC3CJUV Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Armodafinil DCS3BIK Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Arfolitixorin DC4IL27 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + BIO-300 DC76PHF BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Tiagabine DCB9MCK Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Diazoxide DC2HJHE Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Methocarbamol DCQK2HT Methocarbamol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Mebendazole DCQMX55 Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Topotecan DC8X7V4 Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Trimethobenzamide DCW40PR Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Maprotiline DCADJ81 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Acetohexamide DCZBESG Acetohexamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Leflunomide DCJXE63 Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Amantadine DCS3NAS Amantadine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Asenapine DCHOFPA Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Quinine DCONARY Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Endoxifen DCD79QN Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Mycophenolic acid DCU1R4F Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Hydralazine DCKWUMM Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Doxorubicin DC2ZHYA Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Iloprost DCDTK2Q Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Sumatriptan DC5EGEL Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Auranofin DCOOKSK Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Vorinostat DC82CVB Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Estramustine DCT87WW Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Cerivastatin DCVPV5T Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + GSK2194069 DC52JEQ GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Azatadine + Cytarabine DC2K8ZZ Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Azatadine DCVQ4KT Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Carglumic acid + Azatadine DCJAFRU Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cerivastatin + Azatadine DCS10ET Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dantrolene + Azatadine DCMXY3B Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dihydroergotamine + Azatadine DC3R8WC Dihydroergotamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Eptifibatide + Azatadine DCHES2M Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fomepizole + Azatadine DCZUZZX Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Hyodeoxycholic acid + Azatadine DC3BA4N Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Imatinib + Azatadine DCHN09A Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Itraconazole + Azatadine DCEFJYE Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Lacosamide + Azatadine DCD1V2G Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Azatadine DCUN30U Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maraviroc + Azatadine DC8PCN5 Maraviroc Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Memantine + Azatadine DCFWW10 Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metyrosine + Azatadine DCXK0T6 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Azatadine DCF0BNA Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Naringenin + Azatadine DCW90PT Naringenin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Norcisapride + Azatadine DCCWIZG Norcisapride Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Raltegravir + Azatadine DCKLQVU Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ribavirin-TP + Azatadine DCUFPWB Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Azatadine DCMMUKK Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vinblastine + Azatadine DC7JSV5 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 61 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7119).
2 Azatadine FDA Label
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.