Details of the Drug Combinations

General Information of This Drug (ID: DMZHUO5)

Drug Name
Phenylephrine   DMZHUO5
Synonyms
Cyclomydril; Dilatair; Dionephrine; Doktors; Duration; Fenilefrina; Isophrim; Isophrin; Mesaton; Mesatone; Mesatonum; Metaoxedrin; Metaoxedrine; Metaoxedrinum; Metasympatol; Metasynephrine; Metsatonum; Mezaton; Mydfrin; Neofrin; Neosynephrine; Nostril; Ocugestrin; Phenoptic; Phenylephrinum; Spersaphrine; Visadron; Alcon Efrin; Isopto Frin; Minims Phenylephrine; Nostril Spray Pump; Nostril Spray Pump Mild; Phenylephrine Minims; Prefrin Liquifilm; Relief Eye Drops for Red Eyes; Alconefrin Nasal Drops 12; Alconefrin Nasal Drops 25; Alconefrin Nasal Drops 50; Alconefrin Nasal Spray 25; Ah-Chew; Ak-dilate; Ak-nefrin; Fenilefrina [INN-Spanish]; I-Phrine; L-Phenylephedrine; L-Phenylephrine; M-Methylaminoethanolphenol; M-Oxedrine; M-Sympathol; M-Sympatol; M-Synephrine; Mydfrin (TN); Neo-Synephrine; Neo-Synephrine Nasal Drops; Neo-Synephrine Nasal Jelly; Neo-Synephrine Nasal Spray; Ocu-Phrin Sterile Eye Drops; Phenylephrine (INN); Phenylephrine Minims (TN); Phenylephrine [INN:BAN]; Phenylephrinum [INN-Latin]; R(-)-Phenylephrine; L-(3-Hydroxyphenyl)-N-methylethanolamine; L-1-(m-Hydroxyphenyl)-2-methylaminoethanol; L-m-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol; L-alpha-Hydroxy-beta-methylamino-3-hydroxy-L-ethylbenzene; Tannins, compds. with (R)-3-hydroxy-alpha-((methylamino)methyl)benzenemethanol; Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, (R)-(9CI); (-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol; (R)-2-Hydroxy-2-(3-hydroxyphenyl)-N-methylethylamine; (R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol; 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol
Indication
Disease Entry ICD 11 Status REF
Allergic rhinitis CA08.0 Approved [1]
Arrhythmia BC9Z Approved [1]
Common cold CA00 Approved [1]
Cough MD12 Approved [1]
Fecal incontinence ME07 Approved [2]
Fever MG26 Approved [1]
Headache 8A80-8A84 Approved [1]
Mydriasis LA11.62 Approved [1]
Ophthalmic graves disease 5A02.0 Approved [3]
Proctitis DB33.Z Approved [1]
Rhinitis FA20 Approved [1]
Seasonal allergic rhinitis CA08.01 Approved [1]
Vasomotor/allergic rhinitis CA08 Approved [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Ophthalmologicals
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

9 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Epinephrine + Phenylephrine DC1U11I Epinephrine Intracranial Aneurysm [4]
Isoproterenol + Phenylephrine DC814W2 Isoproterenol Postural Tachycardia Syndrome [5]
Loratadine + Phenylephrine DCPQLSE Loratadine Seasonal Allergic Rhinitis [6]
Oxytocin + Phenylephrine DCBP3YY Oxytocin Postpartum Hemorrhage [7]
Tropicamide + Phenylephrine DCISIDC Tropicamide Intraocular Pressure [8]
Urapidil + Phenylephrine DC7SYGS Urapidil Aging [9]
Acetaminophen + Phenylephrine DC4ASAU Acetaminophen Common Cold [10]
Norepinephrine + Phenylephrine DC2SEXK Norepinephrine Hypotension [11]
Levobupivacaine + Phenylephrine DCKMRGW Levobupivacaine Hypotension [12]
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⏷ Show the Full List of 9 DrugCom(s)

References

1 Isoproterenol FDA Label
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019494)
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 485).
4 ClinicalTrials.gov (NCT02701582) Goal-Directed Intraoperative Fluid Management Using FloTrac Monitoring in High-Risk Neurosurgical Patients
5 ClinicalTrials.gov (NCT02673996) POTS Adrenergic Ab (CIHR Aims #1&2)
6 ClinicalTrials.gov (NCT01413958) Effects of Phenylephrine Extended-Release Tablets on Allergy-Related Nasal Congestion (P08498 AM1)
7 ClinicalTrials.gov (NCT06285396) Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro Study
8 ClinicalTrials.gov (NCT03139708) The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients
9 ClinicalTrials.gov (NCT02857153) Effect of High vs. Low MAP Levels on Clinical Outcomes in Elderly Patients During Noncardiothoracic Surgery
10 ClinicalTrials.gov (NCT05070650) Efficacy and Safety of the Combination of Acetylcysteine, Paracetamol and Phenylephrine for the Treatment of Common Cold
11 ClinicalTrials.gov (NCT03215797) Phenylephrine or Norepinephrine for a Better Hemodynamic Stability
12 ClinicalTrials.gov (NCT02802683) Hemodynamic Impact of Hyperbaric Versus Isobaric for Spinal Anesthesia During Cesarean Delivery