Details of the Drug Combinations

General Information of This Drug (ID: DMZMSCT)

Drug Name
Cilostazol   DMZMSCT
Synonyms
cilostazol; 73963-72-1; Pletal; Cilostazole; Pletaal; Cilostazolum; OPC-13013; Cilostazolum [INN-Latin]; OPC-21; OPC 13013; OPC 21; UNII-N7Z035406B; CHEBI:31401; C20H27N5O2; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone; BRN 3632107; 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one; 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one; 3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone; MLS000028470; Cilostazole; Otsuka brand of cilostazol; C 0737; CL23867; Cilostazol [INN:JAN]; Pleta (TN); Pletal (TN); Pletal, Cilostazol; Cilostazol (JP15/USAN/INN); 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxyl)-3,4-dihydrocarobostyril; 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone; 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one
Indication
Disease Entry ICD 11 Status REF
Intermittent claudication BD40.00 Approved [1]
Therapeutic Class
Vasodilator Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

62 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Cilostazol DCR2339 Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aprepitant + Cilostazol DCZT6GP Aprepitant Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Arfolitixorin + Cilostazol DCMYY9I Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + Cilostazol DCC7ZC5 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + Cilostazol DCXQFSQ Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Busulfan + Cilostazol DCBRJO0 Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilastatin + Cilostazol DCTS0LP Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Mebutamate DCBDB3T Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Triiodothyronine DCWF6VF Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Aliskiren DC13HNK Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Dantrolene DCBVLZL Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Ruxolitinib DCY214U Ruxolitinib Hodgkin lymphoma (Cell Line: L-1236) [2]
Cilostazol + Kanamycin DC59B49 Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Epinephrine DC5ZXBW Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + PMID28460551-Compound-2 DC66NO1 PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + IT-141 DC2KT1P IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + BHV-0223 DC5OBGO BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Itraconazole DC4XDZ8 Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Chlorzoxazone DCQIGZ8 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Galantamine DCIM97Q Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Pentamidine DC5WXXU Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Sulfapyridine DCV40PL Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Triflupromazine DCOM1NW Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Niclosamide DCGKXVB Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Eflornithine DCAXJX0 Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Imatinib DC14EQI Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Probenecid DCJPQGX Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Pramipexole DCTR1QA Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Methylene blue DCCRBRR Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Tropisetron DCU0N3Z Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Artemisinin DCUJDE5 Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Trimethobenzamide DC61HSE Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Leflunomide DCKO1JO Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Brincidofovir DCELNPQ Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Chloroquine DC8NL0A Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Mycophenolic acid DC5KMEY Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Hydralazine DCVNYJM Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Mefloquine DCXSYNS Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Cerivastatin DCPNCG5 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Enoxacin DCGZVQJ Enoxacin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Tetracycline DC4F5LE Tetracycline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + Cilostazol DCM7OI6 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Daidzin + Cilostazol DC57JXI Daidzin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diazoxide + Cilostazol DCIN001 Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Doxorubicin + Cilostazol DC5AMHU Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Etomidate + Cilostazol DCDTXMA Etomidate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Flavonoid derivative 1 + Cilostazol DCWEDL2 Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Gefitinib + Cilostazol DCWOV5U Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydroxychloroquine + Cilostazol DCSTI1U Hydroxychloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
JZL195 + Cilostazol DCZ7H6H JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Cilostazol DCXXKSQ Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Cilostazol DCURJ7R Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metaxalone + Cilostazol DCDJ0R5 Metaxalone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Metyrosine + Cilostazol DCAMYRT Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Miglustat + Cilostazol DCNC0M6 Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nabilone + Cilostazol DCDL8BD Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Picoplatin + Cilostazol DCDGB7C Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Rufinamide + Cilostazol DCBIMLW Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sumatriptan + Cilostazol DCY92KC Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tiagabine + Cilostazol DCLCHBJ Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triapine + Cilostazol DCHLQO4 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vorinostat + Cilostazol DC84FD2 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 62 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7148).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.