Details of the Drug Formulations

General Information of Drug (ID: DM1BV7W)

Drug Name
Aliskiren Drug Info
Synonyms
Rasilez; SPP 100; Rasilez (TN); Tekturna (TN); Aliskiren (USAN/INN); (2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methyl-2-(propan-2-yl)nonanamide; (2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide; (2S,4S,5S,7S)-N-(2-Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]octanamide; Octanamide, .delta.-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-.gamma.-hydroxy-4-methoxy-3-(3-methoxypropoxy)-.alpha.,.zeta.-bis(1-methylethyl)-, [.alpha.S-(alpha.R*,.gamma.R*,.delta.R*,.zeta.R*)]
Indication
Disease Entry ICD 11 Status REF
Hypertension BA00-BA04 Approved [1]
Therapeutic Class
Antihypertensive Agents
Cross-matching ID
PubChem CID
5493444
ChEBI ID
CHEBI:601027
CAS Number
173334-57-1
TTD ID
D03SVX
VARIDT ID
DR00061
INTEDE ID
DR0065
ACDINA ID
D00019

Full List of Drug Formulations Containing This Drug

Aliskiren Hemifumarate eq 150mg base tablet
Company Formulation ID FDA Description
Noden Pharma F23935 Crospovidone; Magnesium Stearate; Microcrystalline Cellulose; Povidone; Silica; Colloidal Anhydrous; Hypromellose; Macrogol; Talc; Iron Oxide, Black (E172); Iron Oxide, Red (E172); Titanium Dioxide (E171)
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Aliskiren Hemifumarate eq 300mg base tablet
Company Formulation ID FDA Description
Noden Pharma F23936 Crospovidone; Magnesium Stearate; Microcrystalline Cellulose; Povidone; Silica; Colloidal Anhydrous; Hypromellose; Macrogol; Talc; Iron Oxide, Black (E172); Iron Oxide, Red (E172); Titanium Dioxide (E171)
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Aliskiren Hemifumarate eq 37.5mg base capsule
Company Formulation ID FDA Description
Noden Pharma F23375 Basic Butylated Methacrylate Copolymer; Basic Colloidal Silicon Dioxide; Crospovidone; Povi Done; Dibutyl Sebacate; Magnesium Stearate; Microcrystalline Cellulose; Sodium Lauryl Sulphate
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Aliskiren 150 mg tablet
Company Formulation ID FDA Description
Avera McKennan Hospital; Noden Pharma USA; Novartis Pharmaceuticals Corporation F00675 Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
Physicians Total Care F00676 Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Silicon dioxide, colloidal
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Aliskiren 300 mg tablet
Company Formulation ID FDA Description
A-S Medication Solutions; Noden Pharma USA; Novartis Pharmaceuticals Corporation F00677 Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
Physicians Total Care F00678 Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Crospovidone; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Silicon dioxide, colloidal
A-S Medication Solutions F00679 Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4812).