Details of the Drug Formulations

General Information of Drug (ID: DM2JGQ3)

Drug Name
Trametinib Drug Info
Synonyms
GSK 1120212; GSK-1120212; GSK1120212; JTP 74057; JTP-74057; Mekinist; Trametinib (GSK1120212); Trametinib (GSK1120212JTP 74057); Trametinib (MEK inhibitor); 33E86K87QN; A1-01871; AK174783; CHEBI:75998; UNII-33E86K87QN
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Approved [1] , [2]
Cross-matching ID
PubChem CID
11707110
ChEBI ID
CHEBI:75998
CAS Number
871700-17-3
TTD ID
D04XVN
ACDINA ID
D00694

Full List of Drug Formulations Containing This Drug

Trametinib 0.5 mg tablet
Company Formulation ID FDA Description
Novartis Pharmaceuticals Corporation F21554 Sodium lauryl sulfate; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Hypromelloses; Microcrystalline cellulose; Polyethylene glycols
GlaxoSmithKline F21553 Sodium lauryl sulfate; Magnesium stearate; Mannitol; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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Trametinib 2 mg tablet
Company Formulation ID FDA Description
GlaxoSmithKline F21556 Sodium lauryl sulfate; Magnesium stearate; Mannitol; Ferric oxide red; Titanium dioxide; Croscarmellose sodium; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
Novartis Pharmaceuticals Corporation F21557 Sodium lauryl sulfate; Magnesium stearate; Mannitol; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Hypromelloses; Microcrystalline cellulose
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Trametinib 1 mg tablet
Company Formulation ID FDA Description
GlaxoSmithKline F21555 Sodium lauryl sulfate; Magnesium stearate; Mannitol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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Trametinib Dimethyl Sulfoxide eq 2mg tablet
Company Formulation ID FDA Description
Novartis F23581 Colloidal Silicon Dioxide; Croscarmellose Sodium; Hypromellose; Magnesium Stearate (Vegetable Source); Mannitol; Microcrystalline Cellulose; Sodium Lauryl Sulfate; Hypromellose; Polyethylene Glycol; Titanium Dioxide; Iron Oxide Red; Polysorbate 80
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Trametinib Dimethyl Sulfoxide eq 0.5mg tablet
Company Formulation ID FDA Description
Novartis F23582 Colloidal Silicon Dioxide; Croscarmellose Sodium; Hypromellose; Magnesium Stearate (Vegetable Source); Mannitol; Microcrystalline Cellulose; Sodium Lauryl Sulfate; Hypromellose; Polyethylene Glycol; Titanium Dioxide; Iron Oxide Yellow
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Trametinib Dimethyl Sulfoxide eq 1mg tablet
Company Formulation ID FDA Description
Novartis F23580 Colloidal Silicon Dioxide; Croscarmellose Sodium; Hypromellose; Magnesium Stearate (Vegetable Source); Mannitol; Microcrystalline Cellulose; Sodium Lauryl Sulfate; Hypromellose; Polyethylene Glycol; Titanium Dioxide
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6495).
2 Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651.