Details of the Drug Formulations

General Information of Drug (ID: DM2POTE)

• Drug Name: Colchicine Drug Info
• Synonyms: Colchicin; Colchicina; Colchicinum; Colchineos; Colchisol; Colchysat; Colcin; Colcrys; Colsaloid; Colstat; Condylon; Goutnil; Kolkicin; LOC; Binds to tubulin; Colchicin [German]; Colchicina [Italian]; Colchicine [JAN]; Inhibits microtubular assembly; Spindle poison; C 9754; Colchicine (TN); Colchicine, Colchicum autumnale; MPC-004; N-Acetyl trimethylcolchicinic acid methylether; Colchicine (JP15/USP); Colchicine, (R)-Isomer; Benzo(a)heptalen-9(5H)-one; Colchicine, (+-)-Isomer; N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide; N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide; N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide; N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[.alpha.]heptalen-7-yl)-acetamide; N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-acetamide; (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; 7-alpha-H-Colchicine; 7.alpha.H-Colchicine; 7alphaH-Colchicine

Indication

Disease Entry	ICD 11	Status	REF
Acute gout flare	FA25.0	Approved	[1]
Acute gouty arthritis	FA25.0	Approved	[2]
Gout	FA25	Approved	[3]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[4]
Familial Mediterranean fever		Investigative	[3]

• Therapeutic Class: Gout Suppressants
• Cross-matching ID:
  PubChem CID: 6167
  ChEBI ID: CHEBI:27882
  CAS Number: 64-86-8
  TTD ID: D09DHY
  VARIDT ID: DR00135
  INTEDE ID: DR0372
  ACDINA ID: D00149

Full List of Drug Formulations Containing This Drug

Colchicine 0.6 mg capsule

Company	Formulation ID	FDA Description
Bryant Ranch Prepack; West-Ward Pharmaceticals	F04891	Anhydrous lactose; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Water; Fd&c red no. 3; Silicon dioxide; Cellulose, microcrystalline; Gelatin; Sodium starch glycolate type a potato
Hikma Americas	F04890	Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Titanium dioxide; Water; Fd&c red no. 3; Silicon dioxide; Cellulose, microcrystalline; Gelatin

Colchicine 0.6 mg tablet

Company	Formulation ID	FDA Description
Amneal Pharmaceuticals	F04893	Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Water; Alcohol; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato; Starch, corn
AR Scientific; Aphena Pharma Solutions-Tennessee; Avera McKennan Hospital; Cardinal Health; Physicians Total Care; Prasco; Proficient Rx; RemedyRepack; Takeda Pharmaceuticals America	F04892	Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato; Starch, corn
American Health Packaging	F04894	Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Carnauba wax; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato; Starch, corn
RemedyRepack	F04895	Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato; Starch, corn

References

• [1] FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (NDA) 022351
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7526).
• [3] Colchicine FDA Label
• [4] ClinicalTrials.gov (NCT04322565) Colchicine Counteracting Inflammation in COVID-19 Pneumonia. U.S. National Institutes of Health.