Details of the Drug Formulations

General Information of Drug (ID: DM2R68E)

• Drug Name: Ramipril Drug Info
• Synonyms: Acovil; Altace; Carasel; Cardace; Delix; Hypren; Hytren; Lostapres; Naprix; Pramace; Quark; Ramace; Ramiprilum; Triatec; Tritace; Vesdil; Zabien; Almirall Brand of Ramipril; Astra Brand of Ramipril; AstraZeneca Brand of Ramipril; Aventis Brand of Ramipril; Aventis Pharma Brand of Ramipril; Hoechst Brand of Ramipril; Monarch Brand of Ramipril; Promed Brand of Ramipril; Ramiprilum [Latin]; HOE 498; HOE498; Altace (TN); Hoe-498; Pramace (discontinued); Tritace (TN); Ramipril (USP/INN); Ramipril [USAN:INN:BAN]; Ramipro, Tritace, Altace, Prilace, Ramipril; N-(1S-carboethoxy-3-phenylpropyl)-S-alanyl-cis,endo-2-azabicyclo[3.3.0]octane-3S-carboxylic Acid; [2s,3as,6as]-1-[(2s)-2-[[(1s)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopen; [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid; (2 S ,3 aS,6 aS)-1[(S)-N-[(S)-1-Carboxy-3-phenylpropyl] alanyl] octahydrocyclopenta [ b ]pyrrole-2-carboxylic acid, 1-ethyl ester; (2S,3aS,6aS)-1-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl) octahydrocyclopenta[b]pyrrole-2-carboxylic acid; (2S,3aS,6aS)-1-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, 1-ethyl ester; (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure; (2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid; (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid; (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (non-preferred name); (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid; (2s,3as,6as)-1((s)-n-((s)-1-carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic; (2s,3as,6as)-1-((s)-2-((s)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)-octahydrocyclopenta[b]p; (2s,3as,6as)-1-[(s)-2-((s)-1-ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]

Indication

Disease Entry	ICD 11	Status	REF
Acute heart failure	BD10-BD13	Approved	[1]
Chronic heart failure	BD1Z	Approved	[2]
Congestive heart failure	BD10	Approved	[3]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[4]
Stroke	8B20	Investigative	[2]

• Therapeutic Class: Antihypertensive Agents
• Cross-matching ID:
  PubChem CID: 5362129
  ChEBI ID: CHEBI:8774
  CAS Number: 87333-19-5
  TTD ID: D01STB
  VARIDT ID: DR00031
  INTEDE ID: DR2648
  ACDINA ID: D00582

Full List of Drug Formulations Containing This Drug

Ramipril 10 mg capsule

Company	Formulation ID	FDA Description
Dr Reddy's Laboratories	F18736	Sodium lauryl sulfate; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Magnesium oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Starch, corn
DirectRX; Teva Pharmaceuticals; Unit Dose Services	F18723	Anhydrous lactose; Sodium stearyl fumarate; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
Lake Eire Medical & Surgical Supply DBA Quality Care Products	F18724	Anhydrous lactose; Sodium stearyl fumarate; Fd&c blue no. 2; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
Apotex	F18726	Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Fd&c red no. 3
DirectRX	F18727	Sodium lauryl sulfate; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Starch, corn
Actavis Pharma; American Health Packaging; Physicians Total Care	F18728	D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Gelatin; Starch, corn
Proficient Rx	F18732	D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Gelatin, unspecified; Starch, corn
Aidarex Pharmaceuticals; Aurobindo Pharma; Blenheim Phamacal; Citron Pharma; Proficient Rx; St Marys Medical Park Pharmacy	F18734	Sodium lauryl sulfate; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Starch, corn
Preferred Pharamaceuticals	F18735	Sodium lauryl sulfate; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Shellac; Starch, corn
Bryant Ranch Prepack	F18737	D&c red no. 28; Fd&c red no. 40; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Gelatin; Starch, corn
BluePoint Laboratories	F18716	D&c red no. 28; D&c yellow no. 10; Fd&c blue no. 1; Titanium dioxide; Gelatin; Starch, corn
Cadila Healthcare; Zydus Pharmaceuticals	F18717	D&c red no. 28; D&c yellow no. 10; Fd&c blue no. 1; Titanium dioxide; Gelatin; Starch, pregelatinized corn
BluePoint Laboratories	F18718	D&c red no. 28; D&c yellow no. 10; Fd&c blue no. 1; Titanium dioxide; Gelatin, unspecified; Starch, corn
American Health Packaging	F18725	D&c red no. 28; D&c yellow no. 10; Fd&c blue no. 1; Titanium dioxide; Gelatin, unspecified; Starch, corn
Camber Pharmaceuticals; Exelan Pharmaceuticals	F18729	D&c red no. 28; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Proficient Rx	F18721	Fd&c blue no. 1; Meglumine; Titanium dioxide; Gelatin; Starch, corn
Lake Eire Medical & Surgical Supply DBA Quality Care Products; Lupin Pharmaceuticals; PD-Rx Pharmaceuticals	F18722	Fd&c blue no. 1; Meglumine; Titanium dioxide; Gelatin; Starch, pregelatinized corn
Dispensing Solution; Medsource Pharmaceuticals; RemedyRepack; West-Ward Pharmaceticals	F18719	D&c red no. 28; Fd&c blue no. 1; Titanium dioxide; Gelatin; Starch, corn
A-S Medication Solutions	F18720	D&c red no. 28; Fd&c blue no. 1; Titanium dioxide; Gelatin, unspecified; Starch, corn
A-S Medication Solutions; Accord Healthcare; Lake Eire Medical & Surgical Supply DBA Quality Care Products	F18730	Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Pfizer Laboratories	F18733	Fd&c blue no. 1; Titanium dioxide; Gelatin, unspecified; Starch, corn
Lake Eire Medical & Surgical Supply DBA Quality Care Products	F18731	Titanium dioxide; Gelatin; Starch, corn

Ramipril 5 mg capsule

Company	Formulation ID	FDA Description
Exelan Pharmaceuticals	F18769	D&c red no. 28; D&c yellow no. 10; D&c red no. 33; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Camber Pharmaceuticals	F18771	D&c red no. 28; D&c yellow no. 10; D&c red no. 33; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
AvKARE	F18773	D&c red no. 28; D&c yellow no. 10; D&c red no. 33; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Aidarex Pharmaceuticals; Aurobindo Pharma; Citron Pharma; St Marys Medical Park Pharmacy	F18775	Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Starch, corn
A-S Medication Solutions; Bryant Ranch Prepack; Preferred Pharamaceuticals	F18776	Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 1; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Shellac; Starch, corn
Actavis Pharma; American Health Packaging; Physicians Total Care; Proficient Rx	F18770	D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Titanium dioxide; Gelatin; Starch, corn
Rebel Distributors	F18777	D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Titanium dioxide; Gelatin; Starch, corn
Dr Reddy's Laboratories	F18778	Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide red; Ferrosoferric oxide; Magnesium oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Apotex	F18767	Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Fd&c red no. 3
Proficient Rx	F18763	Fd&c red no. 40; Fd&c blue no. 1; Meglumine; Titanium dioxide; Gelatin; Starch, corn
DirectRX; Lupin Pharmaceuticals	F18764	Fd&c red no. 40; Fd&c blue no. 1; Meglumine; Titanium dioxide; Gelatin; Starch, pregelatinized corn
Cardinal Health; West-Ward Pharmaceticals	F18758	D&c red no. 28; Fd&c blue no. 1; Fd&c yellow no. 6; Titanium dioxide; Gelatin; Starch, corn
A-S Medication Solutions	F18759	D&c red no. 28; Fd&c blue no. 1; Fd&c yellow no. 6; Titanium dioxide; Gelatin, unspecified; Starch, corn
BluePoint Laboratories	F18760	Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 6; Titanium dioxide; Gelatin; Starch, corn
Cadila Healthcare; Zydus Pharmaceuticals	F18761	Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 6; Titanium dioxide; Gelatin; Starch, pregelatinized corn
BluePoint Laboratories	F18762	Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 6; Titanium dioxide; Gelatin, unspecified; Starch, corn
American Health Packaging	F18766	Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 6; Titanium dioxide; Gelatin, unspecified; Starch, corn
Atlantic Biologicals	F18768	D&c red no. 28; Fd&c blue no. 1; Fd&c yellow no. 6; Titanium dioxide; Gelatin; Starch, corn
Teva Pharmaceuticals; Unit Dose Services	F18765	Anhydrous lactose; Sodium stearyl fumarate; Ferric oxide red; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
A-S Medication Solutions; Accord Healthcare	F18772	Fd&c red no. 40; Fd&c blue no. 1; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Pfizer Laboratories	F18774	Fd&c red no. 40; Fd&c blue no. 1; Titanium dioxide; Gelatin, unspecified; Starch, corn

Ramipril 2.5 mg capsule

Company	Formulation ID	FDA Description
Aurobindo Pharma; Avera McKennan Hospital; Citron Pharma	F18753	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Starch, corn
Bryant Ranch Prepack; Proficient Rx	F18754	Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin, unspecified; Shellac; Starch, corn
Dr Reddy's Laboratories	F18756	Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Magnesium oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Exelan Pharmaceuticals	F18748	D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Ferrosoferric oxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Actavis Pharma; American Health Packaging; Physicians Total Care	F18749	D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Ferric oxide yellow; Titanium dioxide; Gelatin; Starch, corn
Camber Pharmaceuticals	F18750	D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Ferrosoferric oxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Rebel Distributors	F18755	D&c red no. 28; D&c yellow no. 10; Fd&c red no. 40; Ferric oxide yellow; Titanium dioxide; Gelatin; Starch, corn
Proficient Rx	F18739	D&c yellow no. 10; Fd&c red no. 40; Meglumine; Titanium dioxide; Gelatin; Starch, corn
Lupin Pharmaceuticals; PD-Rx Pharmaceuticals	F18740	D&c yellow no. 10; Fd&c red no. 40; Meglumine; Titanium dioxide; Gelatin; Starch, pregelatinized corn
Teva Pharmaceuticals	F18745	Anhydrous lactose; Sodium stearyl fumarate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin; Shellac; Starch, corn
Accord Healthcare; Proficient Rx	F18751	D&c yellow no. 10; Fd&c red no. 40; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Cadila Healthcare; Zydus Pharmaceuticals	F18741	D&c yellow no. 10; Fd&c red no. 40; Titanium dioxide; Gelatin; Starch, pregelatinized corn
BluePoint Laboratories	F18742	D&c yellow no. 10; Fd&c red no. 40; Titanium dioxide; Gelatin, unspecified; Starch, corn
American Health Packaging	F18746	D&c yellow no. 10; Fd&c red no. 40; Titanium dioxide; Gelatin, unspecified; Starch, corn
Pfizer Laboratories	F18752	D&c yellow no. 10; Fd&c red no. 40; Titanium dioxide; Gelatin, unspecified; Starch, corn
Cardinal Health; West-Ward Pharmaceticals	F18743	Fd&c yellow no. 6; Titanium dioxide; Gelatin; Starch, corn
A-S Medication Solutions	F18744	Fd&c yellow no. 6; Titanium dioxide; Gelatin, unspecified; Starch, corn
Apotex	F18747	Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Fd&c red no. 3

Ramipril 1.25 mg capsule

Company	Formulation ID	FDA Description
Dr Reddy's Laboratories	F18714	Sodium lauryl sulfate; Butyl alcohol; Isopropyl alcohol; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Magnesium oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Alcohol; Gelatin; Shellac; Starch, corn
Cadila Healthcare; Zydus Pharmaceuticals	F18703	Fd&c red no. 40; Fd&c yellow no. 5; Fd&c yellow no. 6; Titanium dioxide; Gelatin; Starch, pregelatinized corn
BluePoint Laboratories	F18704	Fd&c red no. 40; Fd&c yellow no. 5; Fd&c yellow no. 6; Titanium dioxide; Gelatin, unspecified; Starch, corn
American Health Packaging	F18706	Fd&c red no. 40; Fd&c yellow no. 5; Fd&c yellow no. 6; Titanium dioxide; Gelatin, unspecified; Starch, corn
Aurobindo Pharma; Citron Pharma	F18713	Sodium lauryl sulfate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Silicon dioxide; Gelatin; Shellac; Starch, corn
Exelan Pharmaceuticals	F18708	D&c yellow no. 10; Fd&c yellow no. 6; Ferrosoferric oxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Camber Pharmaceuticals	F18709	D&c yellow no. 10; Fd&c yellow no. 6; Ferrosoferric oxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
West-Ward Pharmaceticals	F18701	D&c yellow no. 10; Fd&c yellow no. 6; Titanium dioxide; Gelatin; Starch, corn
Carilion Materials Management	F18702	D&c yellow no. 10; Fd&c yellow no. 6; Titanium dioxide; Gelatin, unspecified; Starch, corn
Lupin Pharmaceuticals	F18705	Meglumine; Ferric oxide yellow; Titanium dioxide; Gelatin; Starch, pregelatinized corn
Apotex	F18707	Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide
Accord Healthcare	F18710	Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Gelatin; Shellac; Starch, corn
Actavis Pharma; American Health Packaging; Physicians Total Care	F18711	Ferric oxide yellow; Titanium dioxide; Gelatin; Starch, corn
Pfizer Laboratories	F18712	Ferric oxide yellow; Titanium dioxide; Gelatin, unspecified; Starch, corn

Ramipril 2.5 mg tablet

Company	Formulation ID	FDA Description
Cadila Healthcare; Zydus Pharmaceuticals	F18757	Sodium stearyl fumarate; Ferric oxide red; Ferric oxide yellow; Cellulose, microcrystalline; Hypromelloses; Starch, pregelatinized corn

Ramipril 1.25 mg tablet

Company	Formulation ID	FDA Description
Cadila Healthcare; Zydus Pharmaceuticals	F18715	Sodium stearyl fumarate; Ferric oxide yellow; Cellulose, microcrystalline; Hypromelloses; Starch, pregelatinized corn

Ramipril 5 mg tablet

Company	Formulation ID	FDA Description
Cadila Healthcare; Zydus Pharmaceuticals	F18779	Sodium stearyl fumarate; Ferric oxide red; Cellulose, microcrystalline; Hypromelloses; Starch, pregelatinized corn

Ramipril 10 mg tablet

Company	Formulation ID	FDA Description
Cadila Healthcare; Zydus Pharmaceuticals	F18738	Sodium stearyl fumarate; Cellulose, microcrystalline; Hypromelloses; Starch, pregelatinized corn

References

• [1] FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 202392.
• [2] Ramipril FDA Label
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6339).
• [4] ClinicalTrials.gov (NCT04366050) Ramipril for the Treatment of COVID-19. U.S. National Institutes of Health.