Details of the Drug Formulations

General Information of Drug (ID: DM4BDON)

• Drug Name: Methylprednisolone Drug Info
• Synonyms: Depo-medrol; M-predrol; Medrol; Medrol Acetate

Indication

Disease Entry	ICD 11	Status	REF
Acute adrenal insufficiency		Approved	[1]
Acute asthma	CA23	Approved	[1]
Addison disease	5A74.0	Approved	[1]
Allergic rhinitis	CA08.0	Approved	[1]
Angioedema	4A00.15	Approved	[1]
Aspiration pneumonitis		Approved	[1]
Autoimmune haemolytic anaemia	3A20	Approved	[1]
Bursitis		Approved	[1]
Cerebral edema	8D60.1	Approved	[1]
Chronic graft versus host disease		Approved	[1]
Congenital adrenal hyperplasia	5A71.01	Approved	[1]
Crohn disease	DD70	Approved	[1]
Dermatitis herpetiformis	EB44	Approved	[1]
Diamond-Blackfan anemia		Approved	[1]
Disorder of orbital region		Approved	[1]
Epicondylitis		Approved	[1]
Erythema multiforme		Approved	[1]
Exanthem		Approved	[1]
Fever	MG26	Approved	[1]
Granuloma annulare		Approved	[1]
Inflammatory bowel disease	DD72	Approved	[1]
Ischemia-reperfusion injury	DB98.B	Approved	[1]
Leukemia		Approved	[1]
Lupus nephritis	4A40.0Y	Approved	[1]
Microscopic polyangiitis		Approved	[1]
Miliary tuberculosis		Approved	[1]
Multiple sclerosis	8A40	Approved	[1]
Mycosis fungoides	2B01	Approved	[1]
Myeloproliferative neoplasm	2A20	Approved	[1]
Pneumocystis pneumonia	CA40.20	Approved	[1]
Primary cutaneous T-cell lymphoma		Approved	[1]
Psoriasis	EA90	Approved	[1]
Psoriatic arthritis	FA21	Approved	[1]
Rheumatic heart disease		Approved	[1]
Rheumatoid arthritis	FA20	Approved	[2]
Sarcoidosis	4B20.5	Approved	[1]
Seasonal allergic rhinitis	CA08.01	Approved	[1]
Serum sickness		Approved	[1]
Severe asthma	CA23	Approved	[1]
Skin disease	EA00-EM0Z	Approved	[1]
Solid tumour/cancer	2A00-2F9Z	Approved	[2]
Systemic lupus erythematosus	4A40.0	Approved	[1]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 3	[3]
Acquired thrombocytopenia		Investigative	[1]
Asthma	CA23	Investigative	[1]
Beta-thalassemia major		Investigative	[1]
Classic Hodgkin lymphoma		Investigative	[1]
Follicular lymphoma	2A80	Investigative	[1]
Perennial allergic rhinitis	CA08.03	Investigative	[1]
Spinal cord injury	ND51.2	Investigative	[4]
Synovitis		Investigative	[1]
Trichinellosis		Investigative	[1]

• Therapeutic Class: Anticancer Agents
• Cross-matching ID:
  PubChem CID: 6741
  ChEBI ID: CHEBI:6888
  CAS Number: 83-43-2
  TTD ID: D08PIQ
  VARIDT ID: DR00128
  INTEDE ID: DR1056
  ACDINA ID: D00420

Full List of Drug Formulations Containing This Drug

Methylprednisolone 4 mg tablet

Company	Formulation ID	FDA Description
Actavis Pharma	F13646	Stearic acid; Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline; Polacrilin potassium; Sodium starch glycolate type a potato
Physicians Total Care	F13652	Stearic acid; Anhydrous lactose; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
RemedyRepack	F13651	Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Bryant Ranch Prepack; RemedyRepack; Unit Dose Services	F13653	Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
NuCare Pharmaceuticals	F13647	Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline; Polacrilin potassium; Sodium starch glycolate type a potato
RemedyRepack	F13648	Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
American Health Packaging; Avera McKennan Hospital; Major Pharmaceuticals; McKesson; PD-Rx Pharmaceuticals	F13649	Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato
Preferred Pharamaceuticals	F13650	Magnesium stearate; Microcrystalline cellulose; Sodium starch glycolate type a potato
Greenstone; Pharmacia and Upjohn Company; RemedyRepack	F13645	Lactose, unspecified form; Calcium stearate; Sucrose; Starch, corn

Methylprednisolone 16 mg tablet

Company	Formulation ID	FDA Description
Jubilant Cadista Pharmaceuticals; Kaiser Foundation Hospitals	F13639	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Pharmacia and Upjohn Company	F13637	Lactose, unspecified form; Calcium stearate; Sucrose; Mineral oil; Starch, corn
Greenstone	F13638	Lactose, unspecified form; Calcium stearate; Sucrose; Mineral oil; Starch, corn

Methylprednisolone 32 mg tablet

Company	Formulation ID	FDA Description
Jubilant Cadista Pharmaceuticals	F13643	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
RemedyRepack	F13644	Lactose; Calcium stearate; Fd&c yellow no. 6; Sorbic acid; Sucrose; Mineral oil; Starch, corn
Pharmacia and Upjohn Company	F13641	Lactose, unspecified form; Calcium stearate; Sucrose; Mineral oil; Starch, corn
Greenstone	F13642	Lactose, unspecified form; Calcium stearate; Sucrose; Mineral oil; Starch, corn

Methylprednisolone 2 mg tablet

Company	Formulation ID	FDA Description
Pharmacia and Upjohn Company	F13640	Lactose, unspecified form; Calcium stearate; Sorbic acid; Sucrose; Mineral oil; Starch, corn

Methylprednisolone 8 mg tablet

Company	Formulation ID	FDA Description
Greenstone; Pharmacia and Upjohn Company	F13654	Lactose, unspecified form; Calcium stearate; Sucrose; Starch, corn

References

• [1] Methylprednisolone FDA Label
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [3] ClinicalTrials.gov (NCT04341038) Clinical Trial to Evaluate Methylprednisolone Pulses and Tacrolimus in Patients With COVID-19 Lung Injury
• [4] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7088).