Details of the Drug Formulations

General Information of Drug (ID: DM58WKG)

• Drug Name: Panobinostat Drug Info
• Synonyms: Faridak; LBH 589; LBH589; LBH-589; LBH-589B; NVP-LBH589; NVP-LBH-589; Panobinostat, NVP-LBH589, LBH589; (E)-N-HYDROXY-3-(4-{[2-(2-METHYL-1H-INDOL-3-YL)-ETHYLAMINO]-METHYL}-PHENYL)-ACRYLAMIDE; (E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide

Indication

Disease Entry	ICD 11	Status	REF
Chronic graft versus host disease		Approved	[1]
Lung cancer	2C25.0	Approved	[1]
Multiple myeloma	2A83	Approved	[2]
Non-small-cell lung cancer	2C25.Y	Approved	[1]
Plasma cell myeloma	2A83.1	Approved	[1]
Primary cutaneous T-cell lymphoma		Approved	[1]
Type-2 diabetes	5A11	Phase 3	[3]
Primary myelofibrosis	2A20.2	Phase 2	[3]

• Cross-matching ID:
  PubChem CID: 6918837
  ChEBI ID: CHEBI:85990
  CAS Number: 404950-80-7
  TTD ID: D0E3SH
  VARIDT ID: DR00181
  INTEDE ID: DR1234
  ACDINA ID: D00507

Full List of Drug Formulations Containing This Drug

Panobinostat 10 mg capsule

Company	Formulation ID	FDA Description
Novartis Pharmaceuticals Corporation	F16474	Magnesium stearate; Mannitol; Cellulose, microcrystalline; Starch, corn

Panobinostat 15 mg capsule

Company	Formulation ID	FDA Description
Novartis Pharmaceuticals Corporation	F16475	Magnesium stearate; Mannitol; Cellulose, microcrystalline; Starch, corn

Panobinostat 20 mg capsule

Company	Formulation ID	FDA Description
Novartis Pharmaceuticals Corporation	F16476	Magnesium stearate; Mannitol; Cellulose, microcrystalline; Starch, corn

Panobinostat Lactate eq 10mg base capsule

Company	Formulation ID	FDA Description
Secura	F23503	Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Pre-Gelatinized Starch; Gelatin; Titanium Dioxide; Fd&C Blue 1; Yellow Iron Oxide

Panobinostat Lactate eq 15mg base capsule

Company	Formulation ID	FDA Description
Secura	F23505	Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Pre-Gelatinized Starch; Gelatin; Titanium Dioxide; Yellow Iron Oxide; Red Iron Oxide

Panobinostat Lactate eq 20mg base capsule

Company	Formulation ID	FDA Description
Secura	F23504	Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Pre-Gelatinized Starch; Gelatin; Titanium Dioxide; Red Iron Oxide

References

• [1] Panobinostat FDA Label
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7489).