Details of the Drug Formulations

General Information of Drug (ID: DM5PDRB)

• Drug Name: Amikacin Drug Info
• Synonyms: Amicacin; Amikacina; Amikacine; Amikacinum; Amikavet; Amikin; Arikace; Briclin; Kaminax; Lukadin; Mikavir; AMIKACIN SULFATE; Amikacin Base; Amikacin Dihydrate; ANTIBIOTIC BB-K8; Amiglyde-V; Amikacin & Tumor Necrosis Factor; Amikacin (USP); Amikacina [INN-Spanish]; Amikacine [INN-French]; Amikacinum [INN-Latin]; Amikin(Disulfate); Antibiotic BB-K 8; BB-K 8; BB-K8; Amiglyde-V (TN); Amikacin (USP/INN); Amikacin [USAN:BAN:INN]; O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-6))-N(sup 3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine; O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine; O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-[6-amino-6-deoxy-.alpha.-D-glucopyranosyl-(1->4)]-1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide; (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide; (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide; 1-N-(L(-)-gamma-Amino-alpha-hydroxybutyryl)kanamycin A

Indication

Disease Entry	ICD 11	Status	REF
Bacteremia	1A73	Approved	[1]
Bacterial infection	1A00-1C4Z	Approved	[2]
Cholangitis		Approved	[1]
Cystic fibrosis	CA25	Approved	[1]
Escherichia coli meningitis		Approved	[1]
Neonatal sepsis		Approved	[1]
Osteomyelitis		Approved	[1]
Pneumonia caused by gram negative bacteria		Approved	[1]
Pseudomonas aeruginosa infectious disease		Approved	[1]
Staphylococcal pneumonia		Approved	[1]
Tuberculosis	1B10-1B1Z	Investigative	[3]

• Therapeutic Class: Antibiotics
• Cross-matching ID:
  PubChem CID: 37768
  ChEBI ID: CHEBI:2637
  CAS Number: 37517-28-5
  TTD ID: D0Y3MO
  INTEDE ID: DR2167
  ACDINA ID: D00832

Full List of Drug Formulations Containing This Drug

Amikacin eq 250mg injectable

Company	Formulation ID	FDA Description
Heritage Pharmaceuticals D/B/A Avet Pharmaceuticals	F23622	Sodium Metabisulfite; Sodium Citrate; Sulfuric Acid
Teva Parenteral Medicines	F23623	Trisodium Citrate Dihydrate; Sodium Metabisulfite; Water; Sulfuric Acid; Sodium Hydroxide

Amikacin 590 mg/8.4 ml injectable

Company	Formulation ID	FDA Description
Insmed orporated	F23621	Dipalmitoylphosphatidylcholine (Dppc); Cholesterol; Sodium Chloride; Sodium Hydroxide; Water

References

• [1] Amikacin FDA Label
• [2] Emerging drugs for bacterial urinary tract infections. Expert Opin Emerg Drugs. 2005 May;10(2):275-98.
• [3] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.