General Information of Drug (ID: DM6034S)

Drug Name
Selegiline Drug Info
Synonyms
selegiline; L-Deprenalin; Emsam; (-)-selegiline; Selegilinum; Selegilina; Carbex; 14611-51-9; Selegilinum [INN-Latin]; Selegilina [INN-Spanish]; UNII-2K1V7GP655; l-E 250; CHEMBL972; CHEBI:9086; N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine; 2K1V7GP655; (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine; Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-, (R)-; selgene; (R)-(-)-N-Methyl-N-(1-phenyl-2-propyl)-2-propinylamin; Selegyline; Zalapar; Selegiline (transdermal, Parkinson's/depression); Zunrisa/Rezonic
Indication
Disease Entry ICD 11 Status REF
Major depressive disorder 6A70.3 Approved [1] , [2]
Skin imperfections EK71 Patented [3]
Chemotherapy-induced nausea MD90 Discontinued in Phase 3 [4]
Cross-matching ID
PubChem CID
26757
ChEBI ID
CHEBI:9086
CAS Number
14611-51-9
TTD ID
D0S2UG
ACDINA ID
D00618

Full List of Drug Formulations Containing This Drug

Selegiline 5 mg capsule
Company Formulation ID FDA Description
Apotex; Lake Eire Medical & Surgical Supply DBA Quality Care Products F19740 Anhydrous citric acid; Stearic acid; Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Water; Alcohol; Cellulose, microcrystalline; Gelatin; Shellac
A-S Medication Solutions F19741 Anhydrous citric acid; Stearic acid; Anhydrous lactose; Butyl alcohol; Fd&c blue no. 1; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Water; Alcohol; Cellulose, microcrystalline; Gelatin; Shellac
Somerset Pharmaceuticals F19737 Anhydrous citric acid; Lactose; Magnesium stearate; Cellulose, microcrystalline
Mylan Pharamceuticals F19739 Anhydrous citric acid; Lactose, unspecified form; Magnesium stearate; Cellulose, microcrystalline
Golden State Medical Supply F19743 Lactose; Magnesium stearate; Citric acid monohydrate; Ferric oxide red; Titanium dioxide; Cellulose, microcrystalline; Gelatin
Carilion Materials Management; Par Pharmaceutical F19742 Lactose; Magnesium stearate; Citric acid monohydrate; Cellulose, microcrystalline
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⏷ Show the Full List of 6 Formulation(s)
Selegiline 1.25 mg tablet
Company Formulation ID FDA Description
Valeant Pharmaceuticals F19738 Aspartame; Mannitol; Citric acid monohydrate; Ferric oxide yellow; Glycerin; Gelatin
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Selegiline 5 mg tablet
Company Formulation ID FDA Description
Mayne Pharma F19744 Stearic acid; Lactose monohydrate; Cellulose, microcrystalline
Mylan Pharamceuticals F19747 Lactose monohydrate; Magnesium stearate; Citric acid monohydrate; Talc; Povidone, unspecified; Starch, corn
Apotex F19745 Anhydrous lactose; Magnesium stearate; Citric acid monohydrate; Cellulose, microcrystalline
Golden State Medical Supply F19746 Anhydrous lactose; Magnesium stearate; Citric acid monohydrate; Microcrystalline cellulose
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6639).
2 ClinicalTrials.gov (NCT00640159) Tolerability and Efficacy of Switch From Oral Selegiline to Orally Disintegrating Selegiline (Zelapar) in Patients With Parkinson's Disease. U.S. National Institutes of Health.
3 Novel monoamine oxidase inhibitors: a patent review (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):91-110.
4 Clinical pipeline report, company report or official report of GlaxoSmithKline.