Details of the Drug Formulations

General Information of Drug (ID: DM8XP26)

Drug Name
Rolapitant Drug Info
Synonyms
Rolapitant; 552292-08-7; Sch 619734; Varubi; UNII-NLE429IZUC; SCH-619734; NLE429IZUC; 914462-92-3; (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one; (5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one; Rolapitant [USAN:INN]; Varuby; Varubi (TN); Rolapitant (USAN/INN); Rolapitant(sch619734); SCHEMBL354305; GTPL5749; CHEMBL3707331; CHEBI:90908; DTXSID90203740; MolPort-035-942-975; EX-A1288; BCP09609; ZINC3816514
Indication
Disease Entry ICD 11 Status REF
Chemotherapy-induced nausea MD90 Approved [1]
Cross-matching ID
PubChem CID
10311306
ChEBI ID
CHEBI:90908
CAS Number
552292-08-7
TTD ID
D0CF0Y
INTEDE ID
DR1437
ACDINA ID
D00605

Full List of Drug Formulations Containing This Drug

Rolapitant Hydrochloride eq 90mg base tablet
Company Formulation ID FDA Description
Tersera F23539 Colloidal Silicon Dioxide; Croscarmellose Sodium; Lactose Monohydrate; Magnesium Stearate; Microcrystalline Cellulose; Povidone; Pregelatinized Starch; Fd&C Blue No. 2-Indigo Carmine Lake; Polyethylene Glycol; Polysorbate 80; Polyvinyl Alcohol; Talc; Titanium Dioxide
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Rolapitant 90 mg tablet
Company Formulation ID FDA Description
TESARO F19394 Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Povidone, unspecified; Starch, corn
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Rolapitant Hydrochloride eq 166.5mg base/92.5ml Emulsion
Company Formulation ID FDA Description
Tersera F23540 Dibasic Sodium Phosphate Anhydrous; Medium Chain Triglycerides; Polyoxyl 15 Hydroxystearate; Sodium Chloride; Soybean Oil; Water For Injection
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5749).