Details of the Drug Formulations

General Information of Drug (ID: DMBR01X)

Drug Name
Brilinta Drug Info
Synonyms
Ticagrelor; 274693-27-5; Brilique; AZD-6140; AZD6140; AZD 6140; AR-C126532XX; UNII-GLH0314RVC; [14C]-Ticagrelor; GLH0314RVC; CHEBI:68558; (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-DIFLUOROPHENYL)CYCLOPROPYL]AMINO]-5-(PROPYLTHIO)-3H-1,2,3-TRIAZOLO[4,5-D]PYRIMIDIN-3-YL]-5-(2-HYDROXYETHOXY)-1,2-CYCLOPENTANEDIOL; (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol; Brilique; AR-C126532; Ticagrelor (USAN/INN); Brilinta/Brilique
Indication
Disease Entry ICD 11 Status REF
Acute coronary syndrome BA41 Approved [1]
Thrombosis DB61-GB90 Approved [2]
Arterial thrombosis DB61-DD30 Phase 3 [3]
Myocardial infarction BA41-BA43 Phase 3 [3]
Peripheral vascular disease BD4Z Investigative [4]
Cross-matching ID
PubChem CID
9871419
ChEBI ID
CHEBI:68558
CAS Number
274693-27-5
TTD ID
D0WF7L
VARIDT ID
DR00077
INTEDE ID
DR1591
ACDINA ID
D00674

Full List of Drug Formulations Containing This Drug

Ticagrelor 60 mg tablet
Company Formulation ID FDA Description
AstraZeneca F21088 Magnesium stearate; Mannitol; Calcium phosphate, dibasic, dihydrate; Ferric oxide red; Ferrosoferric oxide; Talc; Titanium dioxide; Water; Polyethylene glycol 400; Hydroxypropyl cellulose (type h); Hypromelloses; Sodium starch glycolate type a potato
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Ticagrelor 90 mg tablet
Company Formulation ID FDA Description
AstraZeneca F21089 Magnesium stearate; Mannitol; Calcium phosphate, dibasic, dihydrate; Ferric oxide yellow; Talc; Titanium dioxide; Water; Polyethylene glycol 400; Hydroxypropyl cellulose (type h); Hypromelloses; Sodium starch glycolate type a potato
Bryant Ranch Prepack F21090 Magnesium stearate; Mannitol; Calcium phosphate, dibasic, dihydrate; Ferric oxide yellow; Talc; Titanium dioxide; Water; Polyethylene glycol 400; Hydroxypropyl cellulose; Hypromelloses; Sodium starch glycolate type a potato
Cardinal Health F21091 Magnesium stearate; Mannitol; Dibasic calcium phosphate dihydrate; Ferric oxide yellow; Talc; Titanium dioxide; Water; Polyethylene glycol 400; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Sodium starch glycolate type a potato
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References

1 Ticagrelor-Induced Syncope/Bradyarrhythmia. Cureus. 2021 Jan 23;13(1):e12874.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1765).
3 ClinicalTrials.gov (NCT01732822) A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease. U.S. National Institutes of Health.
4 Antithrombotic Therapy for Symptomatic Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis. Drugs. 2022 Aug;82(12):1287-1302.