Details of the Drug Formulations

General Information of Drug (ID: DMBSHMF)

• Drug Name: BOCEPREVIR Drug Info
• Synonyms: Boceprevir; Victrelis; 394730-60-0; SCH 503034; EBP 520; UNII-89BT58KELH; SCH-503034; 89BT58KELH; CHEBI:68621; (1R,2S,5S)-N-(4-amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[N-(tert-butylcarbamoyl)-3-methyl-L-valyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide; 3-{[(1R,2S,5S)-3-[(2S)-2-[(tert-butylcarbamoyl)amino]-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2-yl]formamido}-4-cyclobutyl-2-oxobutanamide

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis C virus infection	1E51.1	Approved	[1]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Investigative	[2]

• Cross-matching ID:
  PubChem CID: 10324367
  ChEBI ID: CHEBI:68621
  CAS Number: 394730-60-0
  TTD ID: D0V3YT
  VARIDT ID: DR01333
  INTEDE ID: DR0218
  ACDINA ID: D00073

Full List of Drug Formulations Containing This Drug

Boceprevir 200 mg capsule

Company	Formulation ID	FDA Description
Merck Sharp & Dohme	F02695	Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c yellow no. 6; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Alcohol; Aluminum oxide; Gelatin, unspecified; Microcrystalline cellulose; Povidone, unspecified; Shellac

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7876).
• [2] Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease. 2020. April 20. doi: https://doi.org/10.1101/2020.04.20.051581