Details of the Drug Formulations

General Information of Drug (ID: DMF8DNE)

• Drug Name: Framycetin Drug Info
• Synonyms: Neomycin; neomycin; NEOMYCIN B; Soframycin; Actiline; Mycifradin; Fradiomycin; Soframycine; Framycetinum; Framycetine; Framicetina; Neomas; Fradiomycinum; Antibiotique; Nivemycin; Actilin; Neolate; Enterfram; Myacyne; Framygen; Caswell No 595; Vonamycin powder V; Neomycin B sulfate; Neomin; Neomcin; Fradiomycin B; Neo-Rx; Neomicina [DCIT]; Framycetinum [INN-Latin]; PIMAVECORT; Neobrettin; Neo-Fradin; 119-04-0; Neomycine [INN-French]; Neomycinum [INN-Latin]; Framycetine [INN-French]; Framicetina [INN-Spanish]; USAF CB-19; Endomixin; Fraquinol; Myacine; Myciguent; NMY; Neobiotic; Neomicina; Neomycinum; Tuttomycin; VONAMYCIN; NEOMYCIN AND POLYMYXIN B SULFATES; NEOMYCIN SULFATE; Neomycin solution; Soframycin Ophthalmic; Antibiotic 10676; Antibiotic produced by Streptomyces decaris Neomycin B; Framycetin (INN); Soframycin (TN); Framycetin [INN:BAN:DCF]; Sofra-Tulle (TN); BDG-(1-4)CYY-(5-1)RIB-(3-1)IDG; BDG-(1-4)NEB-(5-1)RIB-(3-1)NED; (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside; (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol; D-Streptamine, O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-O-beta-D-ribofuranosyl-(1->5)]-O-[2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1->4)]-2-deoxy

Indication

Disease Entry	ICD 11	Status	REF
Acute liver failure	DB91	Approved	[1]
Alcoholic cirrhosis of liver	DB94	Approved	[1]
Bacterial infection	1A00-1C4Z	Approved	[2]
Blepharoconjunctivitis		Approved	[3]
Corneal abrasion	NA06.4	Approved	[3]
Hepatic coma		Approved	[3]
Hepatic encephalopathy	DB99.5	Approved	[3]
Keratitis		Approved	[4]
Urinary tract infection	GC08	Approved	[5]
Uveitis	9A96.Z	Investigative	[3]

• Therapeutic Class: Antibiotics
• Cross-matching ID:
  PubChem CID: 8378
  ChEBI ID: CHEBI:7508
  CAS Number: 119-04-0
  TTD ID: D05JNI
  INTEDE ID: DR2158
  ACDINA ID: D00462

Full List of Drug Formulations Containing This Drug

Neomycin 500 mg tablet

Company	Formulation ID	FDA Description
ECI Pharmaceuticals; Golden State Medical Supply	F15156	Calcium stearate; Povidone; Silicon dioxide
Lannett Company	F15153	Anhydrous lactose; Calcium stearate; Povidone; Alcohol
Hi-Tech Pharmacal; Major Pharmaceuticals	F15155	Calcium stearate; Povidone
Breckenridge Pharmaceutical	F15157	Calcium stearate; Silicon dioxide; Povidone, unspecified
Teva Pharmaceuticals; X-GEN Pharmaceuticals	F15154	Calcium stearate; Povidone k29/32

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 709).
• [2] Drug information of Framycetin, 2008. eduDrugs.
• [3] A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
• [4] Bacterial isolates, antimicrobial susceptibility, and clinical characteristics of bacterial keratitis in dogs presenting to referral practice in Australia. Vet Ophthalmol. 2016 Sep;19(5):418-26.
• [5] Prostatectomy and infection. J Urol. 1971 Dec;106(6):910-2.