Details of the Drug Formulations

General Information of Drug (ID: DMJZHT1)

• Drug Name: Tadalafil Drug Info
• Synonyms: ADCIRCA; Acdirca; Cialis; Tadanafil; Lilly brand of tadalafil; Tadalafil [USAN]; GF 196960; IC 351; ICOS 351; Ic351; Cialis (TN); GF-196960; IC-351; KS-1117; Tadalafil (JAN/USAN/INN); Cialis, GF 196960, IC 351, ICOS 351, Tadalafil; (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione; (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione; (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione

Indication

Disease Entry	ICD 11	Status	REF
Benign prostatic hyperplasia	GA90	Approved	[1]
Erectile dysfunction	HA01.1	Approved	[2]
Plasma cell myeloma	2A83.1	Approved	[1]
Pulmonary hypertension	BB01	Approved	[1]
Priapism		Investigative	[1]

• Therapeutic Class: Antiimpotence Agents
• Cross-matching ID:
  PubChem CID: 110635
  ChEBI ID: CHEBI:71940
  CAS Number: 171596-29-5
  TTD ID: D05MQK
  VARIDT ID: DR01260
  INTEDE ID: DR1525
  ACDINA ID: D00649

Full List of Drug Formulations Containing This Drug

Tadalafil 10 mg tablet

Company	Formulation ID	FDA Description
Stat Rx USA	F20619	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline; Hydroxypropyl cellulose
Bryant Ranch Prepack	F20618	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose

Tadalafil 2.5 mg tablet

Company	Formulation ID	FDA Description
Bryant Ranch Prepack	F20620	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses
Eli Lilly	F20621	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses

Tadalafil 20 mg tablet

Company	Formulation ID	FDA Description
Aphena Pharma Solutions-Tennessee; United Therapeutics	F20624	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Hydroxypropyl cellulose (type h); Hypromellose, unspecified; Microcrystalline cellulose
Avera McKennan Hospital	F20625	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses
Cardinal Health	F20622	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses
Bryant Ranch Prepack	F20623	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses
Bryant Ranch Prepack	F20626	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose

Tadalafil 5 mg tablet

Company	Formulation ID	FDA Description
Cardinal Health	F20627	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses
Bryant Ranch Prepack	F20628	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses
Bryant Ranch Prepack	F20629	Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose

References

• [1] Tadalafil FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7299).