General Information of Drug (ID: DMKJ485)

Drug Name
Pioglitazone Drug Info
Synonyms
111025-46-8; Actos; Pioglitazona; Pioglitazonum; Glustin; Zactos; 105355-27-9; Pioglitazonum [INN-Latin]; Pioglitazona [INN-Spanish]; Duetact; Pioglitazone [INN:BAN]; Pioglitazone [BAN:INN]; 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione; AD-4833; U 72107; CHEBI:8228; Pioglitazone (Actos); HSDB 7322; Actos (TN); 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione; C19H20N2O3S; AD 4833; 5-[4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL]-2,4-THIAZOLIDINEDIONE; U 72107A; Actos; Actost; Glustin (TN); HS-0047; Pioglitazone (INN); U-72107; U72,107A; Zactos (TN); (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione; (+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione; (+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-(9CI); 5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione; 5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione; 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione; 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione; 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione; 5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine-2,4-dione; Linagliptin + pioglitazone; PCG1
Indication
Disease Entry ICD 11 Status REF
Amyotrophic lateral sclerosis 8B60.0 Approved [1]
Diabetic complication 5A2Y Approved [2]
Non-insulin dependent diabetes 5A11 Approved [1]
Type-2 diabetes 5A11 Phase 3 [3]
Endometriosis GA10 Investigative [1]
Obesity 5B81 Investigative [4]
Therapeutic Class
Hypoglycemic Agents
Cross-matching ID
PubChem CID
4829
ChEBI ID
CHEBI:8228
CAS Number
111025-46-8
TTD ID
D03OFF
VARIDT ID
DR00518
INTEDE ID
DR1295
ACDINA ID
D00534

Full List of Drug Formulations Containing This Drug

Pioglitazone 15 mg tablet
Company Formulation ID FDA Description
Avera McKennan Hospital; Mylan Pharamceuticals F17288 Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Hydroxypropyl cellulose (type h); Sodium starch glycolate type a potato
International Laboratories; Teva Pharmaceuticals F17284 Magnesium stearate; Mannitol; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
A-S Medication Solutions; Carilion Materials Management; International Laboratories; RemedyRepack; Torrent Pharmaceuticals F17283 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Actavis Pharma F17285 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type l)
Accord Healthcare; Aurobindo Pharma; Citron Pharma; Lucid Pharma F17286 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose
American Health Packaging; Avera McKennan Hospital; Clinical Solutions Wholesale; Sandoz F17287 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Macleods Pharmaceuticals F17289 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Ranbaxy Pharmaceuticals F17290 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose
Preferred Pharamaceuticals F17291 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (1200000 mw)
Cardinal Health; Dispensing Solution; NuCare Pharmaceuticals; RemedyRepack F17292 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Cadila Healthcare; Zydus Pharmaceuticals F17293 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
American Health Packaging F17294 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (1200000 mw)
Bryant Ranch Prepack F17295 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (1200000 mw)
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⏷ Show the Full List of 13 Formulation(s)
Pioglitazone 30 mg tablet
Company Formulation ID FDA Description
Mylan Pharamceuticals F17301 Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Hydroxypropyl cellulose (type h); Sodium starch glycolate type a potato
A-S Medication Solutions; International Laboratories; Teva Pharmaceuticals F17297 Magnesium stearate; Mannitol; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
A-S Medication Solutions; Cadila Healthcare; Carilion Materials Management; International Laboratories; NuCare Pharmaceuticals; Proficient Rx; Torrent Pharmaceuticals; Zydus Pharmaceuticals F17296 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Actavis Pharma; Preferred Pharamaceuticals F17298 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type l)
Accord Healthcare; Aurobindo Pharma; Citron Pharma; Lucid Pharma F17299 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose
American Health Packaging; Sandoz F17300 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Macleods Pharmaceuticals F17302 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Ranbaxy Pharmaceuticals F17303 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose
Bryant Ranch Prepack F17304 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (1200000 mw)
Cardinal Health; NuCare Pharmaceuticals; Preferred Pharamaceuticals; RemedyRepack F17305 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
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⏷ Show the Full List of 10 Formulation(s)
Pioglitazone 45 mg tablet
Company Formulation ID FDA Description
Mylan Pharamceuticals F17311 Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Hydroxypropyl cellulose (type h); Sodium starch glycolate type a potato
A-S Medication Solutions; International Laboratories; Teva Pharmaceuticals F17307 Magnesium stearate; Mannitol; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
International Laboratories F17306 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Actavis Pharma F17308 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type l)
Aphena Pharma Solutions-Tennessee; Aurobindo Pharma; Citron Pharma; Lucid Pharma F17309 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose
American Health Packaging; Sandoz F17310 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Macleods Pharmaceuticals F17312 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Ranbaxy Pharmaceuticals F17313 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose
Bryant Ranch Prepack F17314 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (1200000 mw)
Cardinal Health; Preferred Pharamaceuticals F17315 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
Cadila Healthcare; Zydus Pharmaceuticals F17316 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose (type h)
A-S Medication Solutions; Torrent Pharmaceuticals F17317 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxymethyl cellulose
Accord Healthcare F17318 Lactose monohydrate; Magnesium stearate; Carboxymethylcellulose calcium; Hydroxypropyl cellulose
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⏷ Show the Full List of 13 Formulation(s)

References

1 Pioglitazone FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2694).
3 ClinicalTrials.gov (NCT01183013) 30 Week Parallel Group Comparison Study of Linagliptin + Pioglitazone (5+15, 5+30 and 5+45 mg) qd Versus Respective Monotherapies, Followed by a Comparison of 5mg+30mg and 5mg+45mg Versus Respective Monotherapies in Type 2 Diabetes for up to 54 Weeks. U.S. National Institutes of Health.
4 Obesity: pathophysiology and clinical management. Curr Med Chem. 2009;16(4):506-21.