Details of the Drug Formulations

General Information of Drug (ID: DMOGFIX)

Drug Name

Eltrombopag Drug Info

Synonyms

Eltrombopag [INN]; SB 497115; SB497115; SB-497115; [1,1'-Biphenyl]-3-carboxylic acid, 3'-[(2Z)-[1-(3,4-dime; Thylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-(9CI); (E)-3\'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2\'-hydroxybiphenyl-3-carboxylic acid

Indication

Disease Entry	ICD 11	Status	REF
Thrombocytopenia	3B64	Approved	[1]
Idiopathic thrombocytopenic purpura	3B64.10	Phase 3	[1]

Cross-matching ID

PubChem CID: 135449332
ChEBI ID: CHEBI:85010
CAS Number: 496775-61-2
TTD ID: D00PEH
VARIDT ID: DR00908
INTEDE ID: DR0569
ACDINA ID: D00225

Full List of Drug Formulations Containing This Drug

Eltrombopag 12.5 mg tablet

Company	Formulation ID	FDA Description
GlaxoSmithKline	F07197	Magnesium stearate; Mannitol; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
Novartis Pharmaceuticals Corporation	F07196	Magnesium stearate; Mannitol; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Eltrombopag 25 mg tablet

Company	Formulation ID	FDA Description
GlaxoSmithKline	F07199	Fd&c yellow no. 6; Magnesium stearate; Mannitol; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
Novartis Pharmaceuticals Corporation	F07198	Magnesium stearate; Mannitol; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Eltrombopag 50 mg tablet

Company	Formulation ID	FDA Description
GlaxoSmithKline; Novartis Pharmaceuticals Corporation	F07200	Fd&c blue no. 2; Magnesium stearate; Mannitol; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Eltrombopag 75 mg tablet

Company	Formulation ID	FDA Description
GlaxoSmithKline; Novartis Pharmaceuticals Corporation	F07201	Magnesium stearate; Mannitol; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Eltrombopag 100 mg tablet

Company	Formulation ID	FDA Description
GlaxoSmithKline	F07202	Magnesium stearate; Mannitol; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Polyethylene glycol 400; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Eltrombopag Olamine eq 50mg acid tablet

Company	Formulation ID	FDA Description
Novartis	F23438	Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Povidone; Sodium Starch Glycolate; Hypromellose; Iron Oxide Black; Polyethylene Glycol 400; Titanium Dioxide; Fd&C Blue No. 2 Aluminum Lake
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Eltrombopag Olamine eq 12.5mg acid tablet

Company	Formulation ID	FDA Description
Novartis	F23441	Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Povidone; Sodium Starch Glycolate; Hypromellose; Iron Oxide Black; Polyethylene Glycol 400; Titanium Dioxide; Polysorbate 80
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Eltrombopag Olamine eq 100mg acid tablet

Company	Formulation ID	FDA Description
Novartis	F23442	Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Povidone; Sodium Starch Glycolate; Polyvinyl Alcohol; Talc; Iron Oxide Black; Polyethylene Glycol 400; Titanium Dioxide; Iron Oxide Yellow; Iron Oxide Black
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Eltrombopag Olamine eq 25mg acid tablet

Company	Formulation ID	FDA Description
Novartis	F23439	Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Povidone; Sodium Starch Glycolate; Hypromellose; Iron Oxide Black; Polyethylene Glycol 400; Titanium Dioxide; Fd&C Yellow No. 6 Aluminum Lake
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Eltrombopag Olamine eq 75mg acid tablet

Company	Formulation ID	FDA Description
Novartis	F23440	Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Povidone; Sodium Starch Glycolate; Hypromellose; Iron Oxide Black; Polyethylene Glycol 400; Titanium Dioxide; Iron Oxide Red
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Eltrombopag Olamine eq 12.5mg acid/packet for suspension

Company	Formulation ID	FDA Description
Novartis	F23959	Mannitol; Sucralose; Xanthan Gum
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Eltrombopag Olamine eq 25mg acid/packet for suspension

Company	Formulation ID	FDA Description
Novartis	F23960	Mannitol; Sucralose; Xanthan Gum
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6961).