Details of the Drug Formulations

General Information of Drug (ID: DMT5GNL)

Drug Name
Romidepsin Drug Info
Synonyms
Chromadax; Istodax; Antibiotic FR 901228; FK 228; FK228; FR 901228; FR901228; HDInhib_000006; Chromadax (TN); FK-228; FK-901228; FR-901228; Istodax (TN); Romidepsin (USAN); Cyclo((2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl), cyclic (35)-disulfide; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide; (1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo(8.7.6)tricos-16-ene-3,6,9,19,22-pentone; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
Indication
Disease Entry ICD 11 Status REF
Cutaneous T-cell lymphoma 2B01 Approved [1]
Gastrin-producing neuroendocrine tumor Approved [2]
Glucagonoma Approved [2]
Insulinoma 2C10.1 Approved [2]
Lung carcinoid tumor Approved [2]
Melanoma 2C30 Approved [2]
Primary cutaneous peripheral T-cell lymphoma not otherwise specified Approved [2]
Primary cutaneous T-cell lymphoma Approved [2]
Urethral cancer 2C93 Approved [2]
Peripheral T-cell lymphoma 2A90.C Phase 3 [3]
Renal cell carcinoma 2C90 Phase 3 [1]
Cross-matching ID
PubChem CID
5352062
ChEBI ID
CHEBI:61080
CAS Number
128517-07-7
TTD ID
D0L7LC
VARIDT ID
DR00233
INTEDE ID
DR1438
ACDINA ID
D01401

Full List of Drug Formulations Containing This Drug

Romidepsin 10mg/2ml solution
Company Formulation ID FDA Description
Teva Pharms Usa F24229 Povidone; Dl-Alpha-Tocopherol; Dehydrated Alcohol; Propylene Glycol
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Romidepsin 27.5mg/5.5ml solution
Company Formulation ID FDA Description
Teva Pharms Usa F24230 Povidone; Dl-Alpha-Tocopherol; Dehydrated Alcohol; Propylene Glycol
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Romidepsin 10mg/vial powder
Company Formulation ID FDA Description
Celgene F23884 Povidone; Propylene Glycol; Dehydrated Alcohol
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References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7006).
2 Romidepsin FDA Label
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)