Details of the Drug Formulations

General Information of Drug (ID: DMUNTE3)

• Drug Name: Estradiol Drug Info
• Synonyms: Aerodiol; Alora; Altrad; Aquadiol; Bardiol; Climaderm; Climara; Compudose; Corpagen; Dermestril; Destradiol; Dihydrofolliculin; Dihydromenformon; Dihydrotheelin; Dihydroxyesterin; Dihydroxyestrin; Dihydroxyoestrin; Dimenformon; Diogyn; Diogynets; Divigel; Elestrin; Encore; Esclim; Estrace; Estraderm; Estradiolo; Estradiolum; Estradot; Estraldine; Estrasorb; Estreva; Estrifam; Estring; Estroclim; Estrodiolum; Estrogel; Estrovite; Evamist; Evorel; Extrasorb; Femanest; Femestral; Femestrol; Fempatch; Femtran; Follicyclin; Gelestra; Ginedisc; Ginosedol; GynPolar; Gynergon; Gynestrel; Gynodiol; Gynoestryl; Innofem; Lamdiol; Macrodiol; Macrol; Menest; Menorest; Microdiol; Nordicol; Oesclim; Oestergon; Oestradiol; Oestradiolum; Oestrogel; Oestroglandol; Oestrogynal; Ovahormon; Ovasterol; Ovastevol; Ovociclina; Ovocyclin; Ovocycline; Ovocylin; Perlatanol; Polyestradiol; Primofol; Profoliol; Progynon; Syndiol; Systen; Tradelia; Trocosone; Vagifem; Vivelle; Zerella; Zesteem; Zesteen; Zumenon; Climara Forte; Component of Menrium; Estraderm MX; Estraderm TTS; Estradiolo [DCIT]; Estradiolum [INN]; Estring vaginal ring; Estrofem Forte; Oestradiol Berco; Oestradiol R; Progynon DH; Sandrena Gel; Sisare Gel; Trial SAT; CMC_11154; Compudose 200; Compudose 365; E 2; E 8875; E0025; Epiestriol 50; Estraderm TTS 100; Estraderm TTS 50; Estrapak 50; Estroclim 50; Estrofem 2; Sandrena 1; [3H]]estradiol; Activella (TN); Alora (TN); Alpha-Oestradiol; AngeliQ (TN); B-Estradiol; Beta-Estradiol; Beta-Oestradiol; Beta-estradiol; Cis-Estradiol; Cis-Oestradiol; Climara (TN); D-Estradiol; D-Oestradiol; Divigel (TN); E(sub 2); Elestrin (TN); Estrace (TN); Estraderm (TN); Estraderm TTS (TN); Estradiol [USAN:INN]; Estradiol acetate (TN); Estradiol cypionate (TN); Estradiol valerate (TN); Estradiol-17 beta; Estradiol-17beta; Estrasorb (TN); Estrasorb Topical (TN); Estring (TN); Estrofem (TN); Estrogel (TN); EvaMist (TN); Femring (TN); Innofem (TN); Menostar (TN); Oestradiol-17beta; Progynon-DH; Progynova (TN); S-21400; SK-Estrogens; SL-1100; VIVELLE-DOT; Vagifem (TN); Vivelle (TN); [3H]-estradiol; Estradiol-17-beta; Estradiol-3,17beta; Oestradiol-17-beta; Vivelle-Dot (TN); D-3,17beta-Estradiol; [2,4,6,7-3H]-E2; 17 beta-Estradiol; 17-.BETA.-Estradiol; 17-beta-OH-estradiol; 17-beta-estradiol; 17.beta.-Estradiol; 17.beta.-Oestradiol; 17b-Oestradiol; 17beta oestradiol; 17beta-Estradiol; 17beta-Oestradiol; 3,17-beta-Estradiol; 3,17-beta-Oestradiol; 3,17.beta.-Estradiol; 3,17beta-Estradiol

Indication

Disease Entry	ICD 11	Status	REF
Acne vulgaris	ED80	Approved	[1]
Breast cancer	2C60-2C65	Approved	[2]
Hot flushes	GA30	Approved	[1]
Infertility	GB04	Approved	[1]
Obsolete atrophic vulva		Approved	[1]
Metastatic prostate carcinoma		Investigative	[1]

• Therapeutic Class: Estrogens
• Cross-matching ID:
  PubChem CID: 5757
  ChEBI ID: CHEBI:16469
  CAS Number: 17916-67-5
  TTD ID: D08QMX
  VARIDT ID: DR00129
  INTEDE ID: DR0007
  ACDINA ID: D00246

Full List of Drug Formulations Containing This Drug

Estradiol 1.25 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F07580	Stearic acid; Vanillin; Lactose; D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Sodium bicarbonate; Titanium dioxide; Ethylcelluloses; Hydroxypropyl cellulose; Hypromellose 2910 (15 mpa.s); Polyethylene glycol; Shellac

Estradiol 0.3 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F07578	Stearic acid; Vanillin; Lactose; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Sodium bicarbonate; Titanium dioxide; Ethylcelluloses; Hydroxypropyl cellulose; Hypromellose 2910 (15 mpa.s); Polyethylene glycol; Shellac

Estradiol 0.625 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F07579	Stearic acid; Vanillin; Lactose; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Sodium bicarbonate; Titanium dioxide; Ethylcelluloses; Hydroxypropyl cellulose; Hypromellose 2910 (15 mpa.s); Polyethylene glycol; Shellac

Estradiol 1 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F07549	Lactose; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Silicon dioxide; Acacia; Starch, corn
Cardinal Health; Kaiser Foundation Hospitals; Mylan Pharamceuticals; PD-Rx Pharmaceuticals	F07565	Anhydrous lactose; Sodium lauryl sulfate; Fd&c red no. 40; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
Kaiser Foundation Hospitals	F07567	Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Aluminum oxide; Sodium starch glycolate type a potato; Starch, corn
Physicians Total Care	F07568	Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Sodium starch glycolate type a potato; Starch, corn
Allergan; Golden State Medical Supply; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Mayne Pharma; NuCare Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx; RemedyRepack; Teva Pharmaceuticals	F07569	Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Silicon dioxide; Sodium starch glycolate type a potato; Starch, corn
PD-Rx Pharmaceuticals	F07570	Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Silicon dioxide; Sodium starch glycolate type a potato; Starch, corn
A-S Medication Solutions; Aidarex Pharmaceuticals; Avera McKennan Hospital; DirectRX	F07561	Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Aluminum oxide; Calcium phosphate, dibasic, anhydrous; Sodium starch glycolate type a potato; Starch, corn
A-S Medication Solutions; AvPAK; Avera McKennan Hospital; Blenheim Phamacal; Bryant Ranch Prepack; Golden State Medical Supply; PD-Rx Pharmaceuticals; Proficient Rx; Raritan Pharmaceuticals; Stat Rx USA; Watson Laboratories	F07563	Anhydrous lactose; D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Polacrilin potassium
Preferred Pharamaceuticals	F07564	Anhydrous lactose; D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Microcrystalline cellulose; Polacrilin potassium
Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors	F07566	Anhydrous lactose; D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Polacrilin potassium
Epic Pharma; Heritage Pharmaceuticals; NuCare Pharmaceuticals	F07562	Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato

Estradiol 2 mg tablet

Company	Formulation ID	FDA Description
Physicians Total Care	F07550	Lactose; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Silicon dioxide; Acacia; Starch, corn
Mylan Pharamceuticals	F07573	Anhydrous lactose; Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
Physicians Total Care	F07575	Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Sodium starch glycolate type a potato; Starch, corn
Allergan; Golden State Medical Supply; Mayne Pharma; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Teva Pharmaceuticals	F07577	Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Dibasic calcium phosphate dihydrate; Silicon dioxide; Aluminum oxide; Sodium starch glycolate type a potato; Starch, corn
A-S Medication Solutions; Aidarex Pharmaceuticals	F07576	Lactose monohydrate; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Silicon dioxide; Aluminum oxide; Calcium phosphate, dibasic, anhydrous; Sodium starch glycolate type a potato; Starch, corn
A-S Medication Solutions; AvPAK; Blenheim Phamacal; Bryant Ranch Prepack; Golden State Medical Supply; PD-Rx Pharmaceuticals; Raritan Pharmaceuticals; Watson Laboratories	F07572	Anhydrous lactose; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Polacrilin potassium
Rebel Distributors	F07574	Anhydrous lactose; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Polacrilin potassium
Epic Pharma; Heritage Pharmaceuticals	F07571	Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato

Estradiol 0.5 mg tablet

Company	Formulation ID	FDA Description
DirectRX	F07553	Lactose monohydrate; D&c red no. 27; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Aluminum oxide; Calcium phosphate, dibasic, anhydrous; Sodium starch glycolate type a potato; Starch, corn
Kaiser Foundation Hospitals; Mylan Pharamceuticals; PD-Rx Pharmaceuticals	F07557	Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline
Physicians Total Care	F07548	Lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Silicon dioxide; Acacia; Starch, corn
Physicians Total Care	F07558	Lactose monohydrate; Magnesium stearate; Anhydrous dibasic calcium phosphate; Silicon dioxide; Sodium starch glycolate type a potato; Starch, corn
Allergan; Bryant Ranch Prepack; Golden State Medical Supply; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Mayne Pharma; Teva Pharmaceuticals	F07560	Lactose monohydrate; Magnesium stearate; Dibasic calcium phosphate dihydrate; Silicon dioxide; Sodium starch glycolate type a potato; Starch, corn
Avera McKennan Hospital; DirectRX; Kaiser Foundation Hospitals	F07559	Lactose monohydrate; Magnesium stearate; Silicon dioxide; Calcium phosphate, dibasic, anhydrous; Sodium starch glycolate type a potato; Starch, corn
Epic Pharma; Heritage Pharmaceuticals	F07554	Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato
AvPAK; Bryant Ranch Prepack; Golden State Medical Supply; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals; Watson Laboratories	F07555	Anhydrous lactose; Magnesium stearate; Cellulose, microcrystalline; Polacrilin potassium
A-S Medication Solutions	F07556	Anhydrous lactose; Magnesium stearate; Microcrystalline cellulose; Polacrilin potassium

Estradiol 0.01 mg tablet

Company	Formulation ID	FDA Description
Amneal Pharmaceuticals	F07551	Lactose monohydrate; Magnesium stearate; Hypromelloses; Polyethylene glycols; Starch, corn
AvKARE	F07552	Lactose monohydrate; Magnesium stearate; Hypromelloses; Polyethylene glycols; Starch, corn

References

• [1] Estradiol FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1013).