Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM07653)

• Drug Name: SULTHIAME Drug Info
• Synonyms: sultiame; SULTHIAME; Ospolot; sultiam; Sulphenyltame; Sulthiamine; Contravul; Trolone; 61-56-3; Sultiamum; Elisal; Conadil; Riker 594; Bayer A-168; Sultiamum [INN-Latin]; Sultiamo [INN-Spanish]; Sulthiame [USAN]; 4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide; UNII-I00Q766CZ2; RP-10284; R-594; EINECS 200-511-0; p-(Tetrahydro-2H-1,2-thiazin-2-yl)benzenesulfonamide, S,S-dioxide; BRN 1222219; Benzenesulfonamide, 4-(tetrahydro-2H-1,2-thiazin-2-yl)-, S,S-dioxide; RP 10284; 4-(1,1-Dioxido-1,2-thiazinan-2-yl)benzenesulfonamide; CHEMBL328560
• Cross-matching ID:
  PubChem CID: 5356
  ChEBI ID: CHEBI:32171
  CAS Number: CAS 61-56-3
  TTD Drug ID: DM07653

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.