General Information of Drug (ID: DM09SW6)

Drug Name
CD4CAR Drug Info
Indication
Disease Entry ICD 11 Status REF
T-cell leukaemia 2A90 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM09SW6

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
T-cell surface glycoprotein CD4 (CD4) TTN2JFW CD4_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
T-cell surface glycoprotein CD4 (CD4) DTT CD4 6.916 5.411 5.066 5.635
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease T-cell leukaemia
ICD Disease Classification 2A90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
T-cell surface glycoprotein CD4 (CD4) DTT CD4 9.36E-04 0.67 2.62
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT03829540) CD4CAR for CD4+ Leukemia and Lymphoma. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of iCell Gene Therapeutics.