Details of the Drug

General Information of Drug (ID: DM09SW6)

Drug Name

CD4CAR

Indication

Disease Entry	ICD 11	Status	REF
T-cell leukaemia	2A90	Phase 1	[1]
------------------------------------------------------------------------------------

Drug Type

CAR T Cell Therapy

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
T-cell surface glycoprotein CD4 (CD4)	TTN2JFW	CD4_HUMAN	Not Available	[2]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

T-cell leukaemia

ICD Disease Classification

2A90

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
T-cell surface glycoprotein CD4 (CD4)	DTT	CD4	9.36E-04	0.67	2.62

Molecular Expression Atlas (MEA)

Jump to Detail Molecular Expression Atlas of This Drug

References

1	ClinicalTrials.gov (NCT03829540) CD4CAR for CD4+ Leukemia and Lymphoma. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of iCell Gene Therapeutics.