Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM0NJWG)

• Drug Name: Human interleukin-2 Drug Info
• Synonyms: Pulmoleukin; Human interleukin-2 (inhaled, renal cell carcinoma); Human IL-2 (inhaled, renal cell carcinoma),Immunservice; Human interleukin-2 (inhaled, renal cell carcinoma), Immunservice

Indication

Disease Entry	ICD 11	Status	REF
Renal cell carcinoma	2C90	Phase 2	[1]

• Cross-matching ID: TTD Drug ID: DM0NJWG

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukin-2 (IL2)	TTF89GD	IL2_HUMAN	Modulator	[2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Interleukin-2 (IL2)	DTT	IL2	0.848	4.548	3.548	4.053

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Renal cell carcinoma
• ICD Disease Classification: 2C90

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Interleukin-2 (IL2)	DTT	IL2	7.64E-01	1.04E-02	0.07

References

• [1] Clinical pipeline report, company report or official report of Immunservice GmbH.
• [2] Clinical pipeline report, company report or official report of Immunservice.