Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM0VKFO)

Drug Name

C-(5-bromo-4,7-dimethoxyindan-1-yl)methylamine Drug Info

Synonyms

2CB-Ind; CHEMBL424890; 912342-23-5; C-(5-bromo-4,7-dimethoxyindan-1-yl)methylamine; DTXSID70582080; BDBM50194751; 1H-Indene-1-methanamine, 5-bromo-2,3-dihydro-4,7-dimethoxy-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 16086368
CAS Number: CAS 912342-23-5
TTD Drug ID: DM0VKFO

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
5-HT 2A receptor (HTR2A)	TTJQOD7	5HT2A_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
5-HT 2A receptor (HTR2A)	DTT	HTR2A	4.84	4.904	4.652	4.129

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
5-HT 2A receptor (HTR2A)	DTT	HTR2A	1.68E-01	-0.3	-0.14
5-HT 2A receptor (HTR2A)	DTT	HTR2A	5.59E-01	0.15	0.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agoni... J Med Chem. 2006 Sep 21;49(19):5794-803.