Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1E4VP)

Drug Name
IL-21 Drug Info
Synonyms BMS-982470
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Phase 2 [1]
Cross-matching ID
TTD Drug ID
DM1E4VP

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin-21 (IL21) TT9QEJ6 IL21_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Interleukin-21 (IL21) DTT IL21 6.109 5.236 5.413 5.904
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Colorectal cancer
ICD Disease Classification 2B91.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin-21 (IL21) DTT IL21 2.92E-02 0.09 1.42
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4987).
2 National Cancer Institute Drug Dictionary (drug id 409696).