Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1JGDM)

Drug Name

Lpc-Ether Drug Info

Synonyms

LPC-ETHER; 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE; LPE; 1-Octadecyl-sn-glycero-3-phosphocholine; AC1L9K7A; CBiol_001783; SCHEMBL11889677; Bio1_000558; Bio1_000069; Bio1_001047; ZINC8860508; DB03633; O-(1-O-Octadecyl-L-glycero-3-phospho)choline; SR-01000946544; SR-01000946544-1; (4S,7R)-4,7-dihydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium 4-oxide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 446876
TTD Drug ID: DM1JGDM

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phospholipase A2 (PLA2G1B)	TT9V5JH	PA21B_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Phospholipase A2 (PLA2G1B)	DTT	PLA2G1B	5.385	3.733	4.178	5.278

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Phospholipase A2 (PLA2G1B)	DTT	PLA2G1B	2.65E-01	-0.08	-0.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.