Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1T9LJ)

Drug Name

PMID23692593C20 Drug Info

Synonyms

Ahx-FSQn(boro)Bpg; GTPL8486; BDBM50434142

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostate specific antigen (KLK3)	TTS78AZ	KLK3_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostate specific antigen (KLK3)	DTT	KLK3	2.524	3.991	2.248	4.76

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostate specific antigen (KLK3)	DTT	KLK3	2.01E-01	-0.04	-0.09

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Structural optimization, biological evaluation, and application of peptidomimetic prostate specific antigen inhibitors. J Med Chem. 2013 Jun 13;56(11):4224-35.