General Information of Drug (ID: DM1ZPGY)

Drug Name
N-phenethylquinoxaline-2-carboxamide Drug Info
Synonyms
N-phenethylquinoxaline-2-carboxamide; CHEMBL245820; N-(2-phenylethyl)quinoxaline-2-carboxamide; N-(2-phenylethyl)-2-quinoxalinecarboxamide; 2-quinoxalinecarboxamide, N-(2-phenylethyl)-; AC1NRYO0; MLS001198127; SCHEMBL7453913; VCRCXANKNYQHIW-UHFFFAOYSA-N; MolPort-002-738-788; HMS2868E05; ZINC4744930; STK783123; BDBM50197271; AKOS001338925; MCULE-6665471272; N~2~-phenethyl-2-quinoxalinecarboxamide; KB-55566; SMR000559426; ST4122831; N-(2-phenylethyl)quinoxalin-2-ylcarboxamide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5300647
TTD Drug ID
DM1ZPGY

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Metabotropic glutamate receptor 1 (mGluR1) TTVBPDM GRM1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Metabotropic glutamate receptor 1 (mGluR1) DTT GRM1 3.888 3.848 3.711 3.678
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Metabotropic glutamate receptor 1 (mGluR1) DTT GRM1 2.31E-01 -0.05 -0.2
Metabotropic glutamate receptor 1 (mGluR1) DTT GRM1 2.46E-02 0.11 0.74
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Structure-activity relationships of novel non-competitive mGluR1 antagonists: a potential treatment for chronic pain. Bioorg Med Chem Lett. 2007 Jan 15;17(2):486-90.