Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM2104G)

Drug Name
(S)-2-amino-2-phenylpropanoic acid Drug Info
Synonyms
13398-26-0; (S)-2-amino-2-phenylpropanoic acid; (2S)-2-amino-2-phenylpropanoic acid; (S)-2-AMINO-2-PHENYL-PROPIONIC ACID; Benzeneacetic acid, a-amino-a-methyl-, (aS)-; (S)-ALPHA-METHYL-PHENYLGLYCINE; 2-phenyl-d-alanine; 2-(s)-phenylalanine; AC1LGXHO; (+)-2-Phenyl-D-alanine; SCHEMBL222049; CHEMBL3085306; CTK4B8907; (S)-2-Methyl-2-phenyl glycine; HTCSFFGLRQDZDE-VIFPVBQESA-N; MolPort-021-795-057; ZINC8461952; KS-00001G1D; AKOS006287023; AB33354; SC-84682; AJ-57568; KB-04049; (+)-(2S)-2-amino-2-phenylpropionic acid; FT-0695117
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
853461
TTD Drug ID
DM2104G

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) TTFK1JQ CA2D1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) DTT CACNA2D1 5.083 4.833 5.343 2.536
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) DTT CACNA2D1 9.36E-01 -0.03 -0.13
Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) DTT CACNA2D1 2.81E-05 -0.15 -0.68
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41.