Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM2B0TJ)

Drug Name
Leukocyte interleukin Drug Info
Synonyms Multikine (TN)
Indication
Disease Entry ICD 11 Status REF
Head and neck cancer 2D42 Phase 1 [1]
Human immunodeficiency virus infection 1C62 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DM2B0TJ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interleukin 2 receptor beta (IL2RB) TT9721Y IL2RB_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Interleukin 2 receptor beta (IL2RB) DTT IL2RB 7.492 7.017 6.785 7.933
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Head and neck cancer
ICD Disease Classification 2D42
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interleukin 2 receptor beta (IL2RB) DTT IL2RB 7.52E-01 -0.06 -1.11
Interleukin 2 receptor beta (IL2RB) DTT IL2RB 1.96E-01 -4.70E-03 -0.01
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT02115919) Safety Study of Multikine in the Treatment of Perianal Warts. U.S. National Institutes of Health.
2 Leukocyte Interleukin, Inj. (LI) augmentation of natural killer cells and cytolytic T-lymphocytes. Immunopharmacol Immunotoxicol. 1995 May;17(2):247-64.