Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM30GV2)

Drug Name

3-(4-aminophenyl)thieno[3,2-c]pyridin-4-amine Drug Info

Synonyms

3-(4-aminophenyl)thieno[3,2-c]pyridin-4-amine; CHEMBL231153; 832694-16-3; Kinome_611; SCHEMBL3531281; CTK3D3472; DTXSID50593932; RSUCBZJSTXEGSF-UHFFFAOYSA-N; BDBM50201316; Thieno[3,2-c]pyridin-4-amine, 3-(4-aminophenyl)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 18450753
CAS Number: CAS 832694-16-3
TTD Drug ID: DM30GV2

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Vascular endothelial growth factor receptor 2 (KDR)	TTUTJGQ	VGFR2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Vascular endothelial growth factor receptor 2 (KDR)	DTT	KDR	1.98E-01	0.11	0.2

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Thienopyridine urea inhibitors of KDR kinase. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1246-9.