General Information of Drug (ID: DM32OQB)

Drug Name
8-benzyl-9H-purine-2,6-diamine Drug Info
Synonyms 8-Benzyl-9H-purine-2,6-diamine; CHEMBL102303; 9H-Purine-2,6-diamine, 8-(phenylmethyl)-; AC1L9X4P; SCHEMBL3923325; 8-benzyl-7H-purine-2,6-diamine; BDBM50059941
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
457735
TTD Drug ID
DM32OQB

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Polypeptide deformylase (PDF) TT9SL3Q DEFM_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Polypeptide deformylase (PDF) DTT PDF 8.87E-16 -0.54 -0.86
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 CoMFA analysis of tgDHFR and rlDHFR based on antifolates with 6-5 fused ring system using the all-orientation search (AOS) routine and a modified c... Bioorg Med Chem. 2010 Feb 15;18(4):1684-701.