Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM34L89)

Drug Name

4,5-Dimethoxy-10H-anthracen-9-one Drug Info

Synonyms

4,5-dimethoxy-10H-anthracen-9-one; CHEMBL125822; 76403-03-7; AC1NRZIP; CTK2G0639; DTXSID90416070; ZINC2540909; BDBM50060856; 4,5-Dimethoxyanthracen-9(10H)-one; 9(10H)-Anthracenone, 4,5-dimethoxy-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5325945
CAS Number: CAS 76403-03-7
TTD Drug ID: DM34L89

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Arachidonate 5-lipoxygenase (5-LOX)	TT2J34L	LOX5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Arachidonate 5-lipoxygenase (5-LOX)	DTT	ALOX5	4.966	5.133	5.358	6.128

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Arachidonate 5-lipoxygenase (5-LOX)	DTT	ALOX5	4.15E-01	-0.06	-0.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Simple analogues of anthralin: unusual specificity of structure and antiproliferative activity. J Med Chem. 1997 Nov 7;40(23):3773-80.