General Information of Drug (ID: DM38ARE)

Drug Name
Gp100:209-217(210M) peptide vaccine Drug Info
Synonyms Gp100 melanoma-associated antigen vaccine, NCI; Gp100:209-217(210M) peptide vaccine (melanoma); Gp100:209-217(210M) peptide vaccine (melanoma), NCI
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DM38ARE

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Melanocytes lineage-specific antigen GP100 (PMEL) TT8MK59 PMEL_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Melanocytes lineage-specific antigen GP100 (PMEL) DTT PMEL 5.885 5.225 6.079 5.959
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 02 Neoplasm
Disease Class ICD-11: 2C82 Prostate cancer
The Studied Tissue Skin
The Studied Disease Melanoma [ICD-11:2C82]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Melanocytes lineage-specific antigen GP100 (PMEL) DTT PMEL 1.08E-03 1.89 1.06
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT00003895) Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma. U.S. National Institutes of Health.
2 National Cancer Institute Drug Dictionary (drug id 476335).