Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM3KCL1)

Drug Name

4-(4-m-Tolylamino-phthalazin-1-yl)-benzamide Drug Info

Synonyms

CHEMBL196025; AC1LR1ZB; 4-(4-m-Tolylamino-phthalazin-1-yl)-benzamide; Oprea1_451204; MolPort-002-560-372; MolPort-000-703-859; ZINC1297754; BDBM50173029; STK846512; AKOS030511153; AKOS005626717; MCULE-6513504515; 4-(4-(m-tolylamino)phthalazin-1-yl)benzamide; AB00109646-01; 4-[4-(3-methylanilino)phthalazin-1-yl]benzamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 1416247
TTD Drug ID: DM3KCL1

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Vascular endothelial growth factor receptor 2 (KDR)	TTUTJGQ	VGFR2_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Vascular endothelial growth factor receptor 2 (KDR)	DTT	KDR	1.98E-01	0.11	0.2

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Arylphthalazines: identification of a new phthalazine chemotype as inhibitors of VEGFR kinase. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4696-8.