Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM3VA8P)

Drug Name
Pyrrolidine derivative 13 Drug Info
Synonyms PMID28906174-Compound-Figure1f
Cross-matching ID
TTD Drug ID
DM3VA8P

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Oxytocin receptor (OTR) TTSCIUP OXYR_HUMAN Antagonist [1]
Vasopressin V1a receptor (V1AR) TT4TFGN V1AR_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Vasopressin V1a receptor (V1AR) DTT AVPR1A 4.689 3.609 4.591 3.878
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vasopressin V1a receptor (V1AR) DTT AVPR1A 8.89E-04 -0.12 -0.34
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A patent review of oxytocin receptor antagonists 2013-2017.Expert Opin Ther Pat. 2017 Dec;27(12):1287-1290.